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The combination of lamotrigine and mild hypothermia prevents ischemia-induced increase in hippocampal glutamate. In the routine setting of the 20-bed orthopaedic ward of a regional hospital in Netherlands, we developed, implemented, and evaluated a new, function-tailored perioperative care pathway for patients receiving total knee replacement (TKR), aimed at faster functional recovery by reduction of inactivity and stimulation of self-efficacy of the patients. Floral nectar concentration and chemical composition of 26 plant species native to the temperate forest of southern South America are reported and the relationships with the flower type are evaluated.

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Experimental transmission of African swine fever virus by the soft tick Ornithodoros (Pavlovskyella) marocanus (Acari: Ixodoidea: Argasidae). A comparison between the baseline photographs and the current clinical findings allows the physician to detect thin malignant melanomas in a curable stage. During and after ascent, a diver is at risk for decompression sickness and pulmonary barotrauma. Variations in function of hydrogen ion concentration in the absorption spectrum of mixtures of nucleic acid with amino acids, peptides, and proteins

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Colony size analysis showed that intermediate-density bands contain cells capable of a few divisions which do not form large colonies. On the fifth day after the initial successful resuscitation from the cardiorespiratory collapse, she manifested generalized seizure activity and abnormal radiological findings, which were found to be consistent with RPLS.

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Results of deposition density on soil for (134)Cs/(137)Cs obtained seemed consistent, comparing obtained results with those measured by the Japanese government. Studies on prevention of diabetogenic effect of alloxan by previous administration of adrenalin

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faecalis, a five-gene cluster forming a transcriptional unit (revealed by Northern blots and primer extension in E. E2F-1 is a potentially novel independent prognostic factor that may identify gastric cancer patients who will likely benefit from adjuvant chemoradiation therapy following curative resection.

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This article presents information on the development of digital radiography and types of digital radiography systems. NGS substantially improved the detection rates of a wide spectrum of mutations in Polish patients with familial breast and/or ovarian cancer. The protein synthesis inhibitors chloramphenicol and terramycin, and light of low intensity were used to retard the rate of chlorophyll formation in illuminated dark grown pea leaves. We assessed linkage disequilibrium, selected single-marker and multimarker tags, and genotyped these markers in several case-control and family-based samples totalling 4,206 Caucasian individuals.

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The observed inheritance, however, does not fit any simple pattern, indicating a substantial degree of etiologic heterogeneity in the alcoholism phenotype, with the ultimate manifestation of the disorder dependent on poorly understood gene-environment interactions. Perioperative management for iatrogenic aortocoronary dissection during percutaneous coronary intervention.

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However, few hominoid fossils are known from Africa during this period. An acid-buffering bioadhesive vaginal tablet was developed for the treatment of genitourinary tract infections. Susceptibility of congenitally athymic (nude) mice to sporotrichosis. Our study documents that AS160 mediates insulin or AMPK-stimulated surface translocation of CD36 in cardiomyocytes.

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The present Monte Carlo simulation study compares the statistical performance of classical estimation techniques with Bayesian estimation using different prior specifications for a two-level SEM with either continuous or ordinal indicators. Antiviral activity of levamisol in experimental forest-spring encephalitis was shown (protection of 35-40 per cent). Moreover, the acquisition of oncogenic H-RasG12V by natural killer (NK) and T lymphocytes had important biological functions in the adopting lymphocytes: the transferred H-RasG12V induced ERK phosphorylation, increased interferon-gamma and tumor necrosis factor-alpha secretion, enhanced lymphocyte proliferation, and augmented NK-mediated target cell killing. A study examining methodological search strategies for identifying research for evidence-based veterinary practice in the CAB Abstracts database is necessary.

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Blood was obtained via jugular venipuncture before surgery (time 0) and at 24, 48, 72, and 96 hours after recovery from anesthesia. Five patients with intestinal endometriosis underwent attempted laparoscopic segmental colon resection. Poly(ADPR)polymerase (poly(ADPR)P) mRNA and enzymatic activity levels were investigated in primary cultures of rat astrocytes and neurons in the absence or presence of basic fibroblast growth factor (bFGF) and nerve growth factor (NGF), respectively.

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Differential Impact of Depressive and Manic Mood States on Alcohol Craving in Comorbid Bipolar Alcoholism: Preliminary Findings. Simulated angles of hip, knee, and ankle joints show a comparable range of motion (ROM) to the experimental walking data measured in healthy subjects. The multi-channel microimmunosensor was prepared in poly (methyl methacrylate) (PMMA) via hot embossing from a brass molding tool. The aim of this case report was to describe the clinical evolution of a 43-year-old woman with AIP and a polyneuropathy. Sympathetic vasomotor tone--time to move beyond the Network Oscillator Hypothesis?

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Synthetic long peptides that contain immunogenic T-cell epitopes have been used to induce activation of antigen-specific CD8 T cells in vitro for immune monitoring or adoptive transfer, or in vivo after peptide vaccination. Abnormality in the P50 auditory-evoked potential gating is an endophenotype associated with schizophrenia. Studies on the effectiveness of sensor monitoring to support people in daily functioning remain scarce. RNA recombination in a coronavirus: recombination between viral genomic RNA and transfected RNA fragments.

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WHO guidelines have the potential to improve care, but macrolevel barriers related to pharmaceutical regulation and distribution continue to contribute to the treatment gap. However, contrary to NIRS hardness, vitreousness was only involved in endosperm reduction and not in the separation between the starchy endosperm and the outer layers. Thus, the proposed treatment may be considered an effective means of reducing the degree of their visual disability.

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Although clopidogrel is often used to prevent the recurrence of noncardiogenic ischemic stroke, the relationship between the response to clopidogrel and CKD is unclear. Our results suggest that serum chitotriosidase activity predicts the risk of new cardiovascular events in the following 4 years. Transcription factor ATF3 partially transforms chick embryo fibroblasts by promoting growth factor-independent proliferation. The fractions surviving after fractionated irradiation were compared with those given single doses. Cartilage erosion was accompanied by chronic osteomyelitis and formation of pannus tissue.

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Similarity or dissimilarity of endometriosis and endometrium was tabulated to judge qualitatively whether the bulk of the evidence supports the notion that endometriosis is an autotransplant. In addition to the previously described 15 domain isoform, SPINK5 encodes a shorter LEKTI isoform composed of only the first 13 domains, as well as a longer isoform carrying a 30-amino-acid residue insertion between the 13th and 14th inhibitory domains. Computed tomography diagnosis of symptomatic right paraduodenal hernia associated with enteric duplication cyst.

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Highly transparent and UV-resistant superhydrophobic SiO(2)-coated ZnO nanorod arrays. Most researchers would agree that tumor cell proliferation indices should be leading candidates in the search for prognostic factors in breast cancer.

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Temporal information processing in ADHD: findings to date and new methods. That differential treatment was sufficient to produce differential instrumental responding in a subsequent test. Pulmonary hypertension (PH) is commonly observed in patients with diffuse parenchymal lung disease (DPLD). Experiment 2 replicated the finding with different stimulation conditions. Economic Outcomes Associated with a Pharmacist-Adjudicated Formulary Consult Service in a Veterans Affairs Medical Center.

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The authors studied the efficacy of intravitreal triamcinolone acetonide in a case series of patients with diffuse diabetic macular edema without evidence of vitreous-macular traction refractory to laser photocoagulation. The fluid infusion rate is titrated up or down hourly to maintain adequate urine output and other endpoints. Tom40 is the major component of the TOM complex and forms the translocation pore. The primary outcome measure was a 100-mm visual analog scale for pain after a 50-foot walk (15.24 m). The correlation of iNOS and cNOS mRNA expression with the development of neurological disease, as well as the enhanced expression of iNOS within brain regions with inflammatory lesions, strongly suggests that NO may contribute to pathogenesis of Borna disease.

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Sensing of peripheral hormones and nutrients by the hypothalamus plays an important role in maintaining peripheral glucose homeostasis. We make recommendations for both content areas that would benefit from further research as well as methodological approaches that will yield important information in this field.

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Participants included 58 healthy, overweight/moderately obese white adults who met predetermined criteria for insulin resistance or insulin sensitivity based on the modified insulin-suppression test. Immunoreactivity to ubiquitin-protein conjugates is present early in the disease process in the brains of scrapie-infected mice.

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In striated muscles of Caenorhabditis elegans, reduction of insulin-like signaling via DAF-2 insulin/IGF receptor or its intramuscular effector PtdIns-3-kinase (PI3K) causes unexpected activation of MAP kinase (MAPK), consequent activation of pre-existing systems for protein degradation, and progressive impairment of mobility. Efficacy of hepatobiliary scintigraphy in the differential diagnosis of neonatal cholestasis and postoperative follow-up after hepatoporto-digestive anastomosis. Analysis of the clinical manifestations and imaging features of Budd-Chiari syndrome: report of 81 cases

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Caries experience in teenagers related to changes in a dental health programme. Practical considerations in the use of TPN include periodic calorie-protein assessment, electrolyte management, and monitoring for drug-TPN interactions. In addition, intercellular space was considerably increased and there were many ectopic cell processes in basal regions of affected areas. Surface-OTR showed no changes after the addition of 1 nM OT at 4 degrees C, and the value after 60 minutes was 8.90 fmol/mg protein.

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Molecular analysis of the yeast Ty4 element: homology with Ty1, copia, and plant retrotransposons. These three inositol lipid kinases were then used to compare their substrate specificities against the four synthetic stereoisomers of dipalmitoyl PtdIns. The elastic properties of an inhomogeneous medium with chaotic structure were derived within the framework of a fractal model using the iterative averaging approach.

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To elucidate the aetiology of periodontitis, this study focused on the adenosine receptor (AR) expression profiles (A1AR, A2AAR, A2BAR and A3AR) in periodontal diseased tissues. Cytomegalovirus may replicate within the lungs both of recipients of transplants and of patients infected with the human immunodeficiency virus (HIV). Cervical cancer (CC) still remains a common and deadly malignancy among females in developing countries. Exercise endurance limits, metabolic, ventilatory and sensation outcomes were determined at rest prior to exercise and at end-exercise endurance limits. Angiographic computed tomography scan localized the sequestrum that embolized the common iliac arteries.

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Comparison between the Gorlin formula and a simplified formula to measure the severity of pulmonic stenosis. The ACGME Outcomes Project was initiated in 1999 with the intent of facilitating such change in medical education. They succeed to accomplish this task, however they lead to a computational burden as we increase the image dimensionality. Intraperitoneal oxidative stress as an oncolytic immunomodulator? Pantoprazole sodium (Protonix) is a proton pump inhibitor (PPI) widely used to treat peptic ulcer and gastroesophageal reflux due to its ability to inhibit gastric acid secretion.

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The bactericidal activity of human serum against Escherichia coli. Along with the prognostic features of cancers, the benign to malignant surgical ratio and diagnostic interval improved over the time periods and for women aged 60 to 69. Histatin 5 binds to Porphyromonas gingivalis hemagglutinin B (HagB) and alters HagB-induced chemokine responses.

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As obesity has increased markedly worldwide, a greater number of patients with severe obesity have been treated with gastric restrictive and/or malabsorptive surgical procedures. These effects were a) dose dependent over the range 0.1 to 1.0 nmol, b) specific for non-NMDA receptors, and c) site specific. Cytotoxicity mediated by unsensitized human peripheral blood mononuclear cells (MNC) directed against the human bladder cancer cell line, 253J, was significantly enhanced when MNC were preincubated with a rabbit anti-253J serum and then washed free of unbound antibody. Although congenital bleeding disorders can manifest in the newborn period, the most common causes of bleeding and thrombosis in neonates are acquired conditions. Less is known how distinct profiles of alcohol use behavior relate to mental health symptoms.

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The influence of plasma free fatty acids and cholesterol on the aggregation of blood platelets in migraine patients. We reported a case of unresectable gastric cancer presenting pylorus stenosis treated orally by S-1 therapy in a 72-year-old man who underwent gastrojejunostomy. Bland-Altman analysis of these data confirmed good agreement between in-clinic and home-based measurements, both across all visits and at the individual visits at study weeks 6, 12, 18, and 52.

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Nano suspension coating method can be introduced as novel method in formulation of CPOPs. We conclude that XRCC2 is important in the early stages of homologous recombination in mammalian cells to facilitate RAD51-dependent recombination repair but that it does not make use of ATP binding to promote this function. Bis-3WJ probes are designed logically to recognize BCR/ABL fusion gene, which forms the stable bis-3WJ nanostructure for the activation of polymerase/nicking enzyme machineries in cascade, resulting in synthesis of DNAzyme subunits. The kinase activity recovered within 9 h after GeO(2) removal and correlated with the transition of G2/M-G1 phase of the cells.

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This procedure permitted the definitive all-ceramic restorations to possess a more uniform shade between teeth restored with metal posts and cores and adjacent vital teeth. Detection of intrauterine growth retardation in twins using individualized growth assessment. Discovery of a genetic polymorphism of human plasma protein C inhibitor (PCI): genetic survey utilizing isoelectric focusing followed by immunoblotting, immunological and biochemical characterization. Quaternary ammonium groups exposed at the surface of silica nanoparticles suitable for DNA complexation in the presence of cationic lipids.

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Transplantation of haemopoietic stem cells containing immunocompetent cells invariably leads to the development of graft versus host disease (GVHD) in the recipients unless immunosuppressive prophylaxis is administered for approximately 6 months. Interestingly, RA potentiates the Nrf2/HO-1 signaling pathway, as shown by immunohistochemical and Western blot analyses. Despite scientific evidence of effectiveness, psychotherapy for personality disorders is not yet fully deployed, nor is its reimbursement self-evident. Incidence and predictors of early left ventricular thrombus after ST-elevation myocardial infarction in the contemporary era of primary percutaneous coronary intervention.

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Parameters of both groups were analyzed before and after surgery with each parameters being tested on correlativity. A vitreous hemorrhage was induced by an experimental incision through the pars plana in the right eye of 24 rats. This was done by introducing two alternative measures of LICI signal amplitude: the Discrete Fourier Transform (DFT) and the Hilbert transform (HT). Increasing understanding of the signal transduction pathways of inflammatory cells involved in the disease suggests that targeting specific kinases and transcriptional regulatory mechanisms may prove improve outcome from sepsis.

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Cells continued to accumulate in mitosis for at least 24 h, indicating that at these low concentrations okadaic acid was not cytotoxic, but rather acted as a cytostatic agent. Transcript levels of TaPP2Ac-1 were examined in wheat responding to water deficit.

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An increase in the ratio of the summating potential to the action potential components of the electrocochleogram is known to be a feature of endolymphatic hydrops. Balancing perioperative risks in orthopedic surgery: the patient with a coronary stent. Epidermal inclusion cyst of the umbilicus following abdominoplasty. Here, using gene insertions and deletions found in the DNA gyrase, GyrA, and in the paralogous DNA topoisomerase, ParC, we present evidence that the root of life is outside the Actinobacteria.

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The recombinant protein was isolated by immunoprecipitation with a specific rabbit antiserum and was shown to have protein tyrosine phosphatase (PTPase) activity. Significantly increased mortality in mice was observed at the various tested dose levels of styrene when challenged with EMCV. Although hFPPS is a well-established therapeutic target for lytic bone diseases, the currently available bisphosphonate drugs exhibit poor cellular uptake and distribution into nonskeletal tissues. No living snails were found in both experimental and control groups three consecutive years after the snail control intervention above mentioned.