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Penile erection is caused by the engorgement of the penis with blood. This engorgement occurs when the blood vessels delivering blood to the penis increase the delivery of blood and the blood vessels carrying blood away from the penis decrease the removal of blood. Under normal conditions, sexual stimulation leads to the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase, which causes the production of cyclic guanosine monophosphate (cGMP). It is the cGMP that is primarily responsible for the erection by affecting the amount of blood that the blood vessels deliver and remove from the penis. Womenra inhibits an enzyme called phosphodiesterase-5 (PDE5) which destroys the cGMP. Thus, Womenra prevents the destruction of cGMP and allows cGMP to accumulate and persist longer. The longer cGMP persists, the more prolonged the engorgement of the penis. The FDA approved Womenra in March 1998.

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Dose-dependent sulfoconjugation of salicylamide in dogs: effect of sulfate depletion or administration. Evaluation of clinical tutors and medical students regarding clinical rotations in primary healthcare centers and hospitals The early response gene IEX-1 modulates apoptosis and cell growth in a poorly defined fashion. Initial studies have yielded opposing results as to the nature of the major repolarizing current(s) in these cells. Haplotyping of these YACs and their mother cell line indicates that the majority of YACs from this region contain deletions.

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The observation that the stereoisomer 9-cis-retinoic acid binds with high affinity to RXRs suggested that this retinoid has a distinct role in controlling RXR activity, but it was almost simultaneously discovered that RXRs function as auxiliary receptors for RARs and related receptors, and are essential for DNA binding and function of those receptors. Identification of the Plant Ribokinase and Discovery of a Role for Arabidopsis Ribokinase in Nucleoside Metabolism. This text explores the reasons for such a development in patients undergoing cardiovascular surgery where the transfusion requirement has drastically declined in recent years. Delivery at 37 weeks produced a healthy girl who required no resuscitation.

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Differentiation of human menstrual blood-derived endometrial mesenchymal stem cells into oocyte-like cells. Phylogenetic analysis of 16S rDNA sequences of Cardinium, Wolbachia, Rickettsia and Arsenophonus showed that each of these bacteria form a separate cluster when compared to their respective counterparts from other parts of the world. Exposure to tellurite in presence of endogenous or exogenous GSH produces marked leakiness which stems from the formation of aqueous leaks permeant to ions and nonelectrolytes and sensitive to inhibition by phloretin.

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As shown here, the model can also be used to simulate grasping movements whose kinematics resemble those of grasps performed by people with spastic hemiparesis. Recently, our group found mutations in CLMP as the cause of the recessive form of CSBS, and mutations in FLNA as the cause of the X-linked form of the disease.

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Fifty-five subjects were divided into two groups according to the body mass index. The present study shows that 2 types of symptoms increased primarily over time: Apathy and Hyperactivity. SNP in differentially methylated region upstream of H19 gene in Chinese Korean nationality Observational study on the dispensing of cough syrups to children with acute cough by community pharmacists in France.

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A field experiment to evaluate various outcomes of continuity of physician care. Optimization of the gas pressure and waveguide configuration has enabled us to produce bright and spatially coherent harmonics extending from the extreme ultraviolet to soft x rays.

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