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Aciklovir (Acyclovir)

Aciklovir is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Aciklovir is converted to an active form by the virus itself, and the virus then uses the active form of Aciklovir rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Aciklovir into new viral DNA stops the production of the DNA. Virally infected cells absorb more Aciklovir than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Aciklovir in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

Similar Products:
Pacifen, Locimez, Triomune, Teraprost, Spiroctan, Caverject, Bactocin, Erbolin, Oxybutynine, Hidroxizina, Pidogrel, Ozid, Frilans, Lomox, Nocid, Obelit, Makrodex, Flumarc, Metrovax, Cyclophosphamide, Aprazol, Oxetol, Probic, Fenax, Alfu, Helicid, Zepatier, Topictal, Lansec, Losec, Altiva, Clarimac, Warfarine, Lufi, Omepron, Tetracon, Tamsol, Lostam, Advagraf, Megaset,

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Diagnostic performance and system delay using telemedicine for prehospital diagnosis in triaging and treatment of STEMI. Isoflurane induces both excitatory and inhibitory actions in the cholinergic arousal system. Serum responses, and in some cases intestinal specific antibodies, were measured out to 33 days post-immunization. Since IL-8 is known to be the major inducer of angiogenesis caused by these cells, we examined the ability of fibrin to stimulate IL-8 expression from OSCC cells in vitro. Protection was manifested by a significant decrease in lesion size (as much as a 30-fold reduction) and parasite burden (as much as a 71-fold reduction).

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Complex revival features of rotational wave packets are obtained from the interplay of a molecular rotational distribution and a measured physical observable. To examine consumptive removals for specific prey, diet compositions were summarized into major prey categories, and predatory removals by marine mammal species as well as for total marine mammal consumption were estimated for each prey taxa. These data suggest that acceptance, in particular, may be a construct that explains some variance in maternal distress. To determine whether there is any difference in infection rate at 90 days between trauma operations performed in laminar flow and plenum ventilation, and whether infection risk is altered following the installation of laminar flow (LF).

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The responsiveness of human dental pulp (HDP) cells to bovine plasma FN was investigated. A pessimistic attitude towards the future and low psychosocial functioning predict psychiatric diagnosis among treatment-seeking adolescents.

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Association of increased myocardial contractility and elevated end-diastolic wall tension with short-term myocardial ischemia: a pressure-volume analysis. The present series was comprised of 15 males (one with bladder NA and recurrence in urethra) and 6 females, with ages ranging from 24 to 79 years (mean 55). In countries where routine vital registration data are scarce, Demographic Surveillance Sites (DSS: locally defined populations under longitudinal surveillance for vital events and other characteristics) and Demographic and Health Surveys (DHS: periodic national cluster samples responding to cross-sectional surveys) have become standard approaches for gathering at least some data.

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Overproduction of a penicillin-binding protein is not the only mechanism of penicillin resistance in Enterococcus faecium. Radiation Therapy Plus Anti-Programmed Death Ligand 1 Immunotherapy: A Review on Overall Survival. We, therefore, hypothesized the role of CIZ/NMP4 in B16 melanoma cells that metastasize to bone. It is concluded that ablation of accessory pathways can be accomplished easily and without risk by means of the radiofrequency catheter technique.

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Action of brief pulses of glutamate on AMPA/kainate receptors in patches from different neurones of rat hippocampal slices. Because the absolute risk of adverse effects of metoprolol is unknown, the clinical relevance of the CYP2D6 genotype for metoprolol therapy has to be determined in a prospective manner. Troglitazone improves ovulation and hirsutism in the polycystic ovary syndrome: a multicenter, double blind, placebo-controlled trial.

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Tracking ability in subjects symptomatic of cumulative trauma disorder: does it relate to disability? The clinical features, pathologic findings, and self-limited course suggested recurrent palmoplantar hidradenitis. Conversely, diminishing cell density, as might occur at a wound front, leads to large, broad collectives with a distinct leader-follower structure. Development of the iliac crest microsurgical free flap has greatly improved the surgical reconstruction of oromandibular defects.

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Mechanism of repression of squamous differentiation marker, SPRR1B, in malignant bronchial epithelial cells: role of critical TRE-sites and its transacting factors. Death was caused by pericardial tamponade combined with bleeding into the pleural cavity. Promoting physical health for people with schizophrenia by reducing disparities in medical and dental care. Thus, ACTH fragments devoid of peripheral endocrine activity reduce pilocarpine-induced epileptiform activity in rats.

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Possible procoagulant roles of microparticles, circulating endothelial cells and endothelial apoptosis, are also discussed. T-cell line-tropic gp120 envelope proteins were at least 10-fold more susceptible to V3 loop proteolytic cleavage by human thrombin, and 1000-fold more susceptible to V3 loop proteolytic cleavage by human mast cell tryptase than macrophage-tropic gp120 envelope proteins. The Snail1 (Snai1) gene promotes epithelial-mesenchymal transitions during development and disease progression, and Snai1 null mouse embryos exhibit defects in gastrulation.

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It is also probable that mitochondria containing monoamine oxidase type B are transported along the axons, but that this enzyme undergoes a change, for example, conformational change, decomposition or removal from the membranes. The glycosylated nature of these proteins was demonstrated by their reactivity with concanavalin A and by selective labeling with the biotin-hydrazide reagent following periodate oxidation.

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Synthesis of 24,28-iminofucosterol and its inhibitory effects on growth and steroid metabolism in the silkworm, Bombyx mori. TaqMan low density array (LDA) is promising for high throughput screening in functional genomics by simultaneously measuring mRNA expression of multiple genes. In the science of microbial pharmacokineticspharmacodynamics (PK-PD), particular antibiotic exposures are related to outcomes such as microbial kill and resistance suppression, which can often be demonstrated in preclinical models.

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Seasonal occupational asthma in an agricultural products merchant--a case report. New oral hypoglycemic drug--gliclazide--in the treatment of maturity onset diabetes mellitus. To examine the effects of administration of L-cystine and/or L-theanine on the balance of T helper (Th) 1/Th2 cell responses, the serum ratios of the Th1 cytokine, interferon (IFN)-gamma, and the Th2 cytokine, interleukin IL-10, were investigated. Inhibition of expression of pancreatic p38 MAPK and JNK and upregulation of ERK1/2 expression by APC treatment may protect against pancreatic injury, thus ameliorating severity of the disease. These effects could not be attributed to prevention of antibody uptake even though in some systems the uptake of antibody was diminished.

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We advocate operating within the first few months of life to lessen amblyopia. Both lumbar epidurals and lumbar plexus nerve blocks have been described for postoperative pain control, but it is unclear if one technique is more beneficial. With the modern flexible instruments available for gastro-intestinal endoscopy, it is possible to reach the oesophagus, stomach, duodenum, colon and ileum. In vitro activity of sparfloxacin and other antimicrobial agents against genital pathogens.

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Inactivation of CYB5R2 is associated with lymph node metastasis in NPC. Diagnosis and surgical treatment of congenital aortic septal defects. Factors contributing to clinical seizure lateralization in patients with mesial temporal lobe epilepsy. In both cases, the proliferating tubules reacted with keratin 903 and were negative for prostate-specific antigen and prostate acid phosphatase, thereby excluding the diagnosis of prostatic adenocarcinoma.

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Discovery of nonpeptidic small-molecule AP-1 inhibitors: lead hopping based on a three-dimensional pharmacophore model. Threatened miscarriage in general practice: diagnostic value of history taking and physical examination. BDIX male rats were given an intra-hepatic injection of a mixture containing DHDK12 tumor cells and xenogeneic fibroblasts. Ligand blotting assays of kidney membrane preparations fractionated by SDS-PAGE revealed that Sepp1 binds megalin, a lipoprotein receptor localized to the proximal tubule epithelium.

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Leaf-disc assay based on transient over-expression in Nicotiana benthamiana to allow functional screening of candidate effectors from aphids. Determination of PKC isoform-specific protein expression in pulmonary arteries of rats with chronic hypoxia-induced pulmonary hypertension. Improvements compared to previous versions are achieved through adequately chosen data structures that facilitate the efficient handling of symmetric sparse matrices. The accuracy of DSE is influenced by the LV geometric pattern and peak wall stress.

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Analysis of clr2 mutant strains revealed a major role for Clr2 in mating-type and rDNA silencing, and weaker effects on centromeric silencing. All patients undergoing colorectal resection with curative intent between 1995 and 1999 at a tertiary referral hospital were retrospectively reviewed. On the other hand serial studies in the same subject can be much more informative because the test is normally highly reproducible if conditions are unchanged. This study compares functional outcome of knee arthrodesis following failed primary arthroplasty with that of revision knee arthroplasty in a matched patient group. Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma.

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Quantitative PCR was used to detect viral replication in MDCC-MSB1 cells, and the viral localization was observed by confocal microscopy. Several of the most common statistical errors and methodological pitfalls that occur in the field of psycho-oncology are discussed, including those that occur at the design, analysis, reporting and conclusion stages.

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In kidney transplantation, the prevalence of hypercholesterolemia as a co-morbidity factor known to affect graft function, is rising due to the increased number of older donors in response to organ shortage as well as to the hyperlipidemic effects of immunosuppressors in recipient. Supporting diagnosis of attention-deficit hyperactive disorder with novelty detection. This is followed by a further phase transition at more negative potentials involving the readsorption of bilayer patches. Intra-articular bipolarradiofrequency thermocoagulation of the thoracic facet joint may be a technically easier and valid method of treating mid back pain of thoracic facet origin.

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Considering the critical role of bcl-2-associated death promoter (BAD) and p53 proteins in DNA damage -induced apoptosis, the aim of this study was to assess the effect of cAMP-elevating agents on these proteins in doxorubicin-treated pre-B acute lymphoblastic leukemia (pre-B ALL) NALM-6 cells.The pre-B ALL cell line NALM-6 was cultured and treated with doxorubicin in combination with or without cAMP-elevating agents forskolin and 3-isobutyl-1-methylxanthine (IBMX). We examined cryptococcal antigenemia as a risk factor for HIV-associated mortality in Indonesia, which is experiencing a rapidly growing HIV epidemic. Both early invasive and in situ adenocarcinoma stained equally intensely with both agents and both antibodies stained diffusely tubal metaplasia, endometrial lined glands, and even occasional areas of normal endocervical mucosa. In contrast with quasi-one-dimensional systems, the resistivity anomaly associated with the CDW transition is strong in the direction perpendicular to the CDW wave vector Q (a axis) and very weak in the CDW wave vector Q direction (c axis). the difference between soda sales tax and the tax on food products generally) and a summary score representing the strength of state laws governing competitive beverages (beverages that compete with the beverages in the federally funded school lunch programme) in US schools.

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Night waking among breastfeeding mothers and infants: Conflict, congruence or both? The interaction of B-cells and PCa may serve as the basis for new therapeutic targets. Highly susceptible HLA haplotypes of type 1 diabetes observed in Caucasian patients are not found in Japanese patients, while protective HLA haplotypes are similar. This would seem to indicate that there may be a carcinogenic role for anthophyllite.

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Evaluation of serum D-dimer, fibrinogen, and CA19-9 for postoperative monitoring and survival prediction in resectable pancreatic carcinoma. Generation of mouse chimeras with high contribution of tetraploid embryonic stem cells and embryonic stem chibroxin 3 mg ulotka pl cell-fibroblast hybrid cells. The lower limit of quantification of erythromycin ethylsuccinate and erythromycin were both 0.5 ng/ml.

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