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The synchronization-desynchronization transition is at the blowout bifurcation which coincides with the hyperchaos-chaos transition. Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities. Potential of the chemical dinotefuran in the control of Rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae) semi-engorged female ticks.

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Three modifications that allowed GaLV Env to pseudotype human immunodeficiency virus type 1 particles were identified: removal of the R peptide (C-terminal half of the cytoplasmic domain), replacement of the whole cytoplasmic tail with the corresponding MuLV region, and mutation of two residues upstream of the R peptide cleavage site. In this regard, commonly abused drugs as well as drug-associated experiences are capable of modifying the phosphorylation of ERK within central reinforcement systems. CALR and MPL mutations were identified by bi-directional Sanger sequencing. The results were compared with those of 16 age-matched healthy control subjects by using Mann-Whitney and Kruskal-Wallis tests.

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Excluding the other causes of exudative ascites, we considered that the ascites was caused by dermatomyositis. Further studies are needed in order to establish a univocal classification of the non-toxic strains that, according to our results, seem to be a paraphyletic group. There was a significant correlation between the BBS and ABC scores and different components of the LOS test.

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This may represent an important mechanism of resistance to antiangiogenic therapies. Our studies identified amino acid residues Leu(172), Thr(281), and Leu(282) in PS1 as necessary for PS1-selective inhibition by ELN318463. Among various potential domains of MUC4, epidermal growth factor (EGF) -like domains are hypothesized to interact with and activate the ErbB2 receptors, suggesting an intramembrane-growth factor function for MUC4.

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To detect linear antigenic epitopes of TSST-1 the reactivity of the sera with 11-meric peptides having an overhang of four residues, covering the entire molecule of TSST-1, have been studied. Further research may validate assessment tools in this population and examine the physiologic, psychologic, and neuro-immune implications of alcohol abuse on patients with MS.

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Hydroxyapatite cement is a calcium phosphate-based material that when mixed with water forms a dense paste that sets within 15 minutes and isothermically converts in vivo to a microporous hydroxyapatite implant. A majority infections caused by dengue virus (DENV) are asymptomatic, but a higher incidence of severe illness, such as dengue hemorrhagic fever, is associated with secondary infections, suggesting that pre-existing immunity plays a central role in dengue pathogenesis. Anti-tumor immune reactivity of lymphocytes derived from lymph nodes regional to and distant from tumor growth, as well as that of peripheral blood leucocytes, against autochthonous tumor cells, was investigated. Despite early successful transplantation, many patients developed a disabling and fatal condition called obliterative bronchiolitis. Treatment of monosymptomatic nocturnal enuresis: sertraline for non-responders to desmopressin.

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The intensities were lower than previously reported in the literature. Physiochemical studies were carried out on the tricarbocyanine dye indocyanine green in biological fluids and organic solvents.

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Oral chronic graft-versus-host disease is a frequent complication of allogeneic hematopoietic stem cell transplantation, contributing to patient morbidity and mortality. These results suggest that the increased HPA axis activity which follows the peripheral IL-1 beta administration, a phenomenon previously shown to depend on endogenous CRF, does not require immediate activation of hypothalamic CRF perikarya. Previous research indicates that bony morphology is associated with an increased risk of injury in other joints (eg, the knee), but the extent to which bony morphology is associated with traumatic GHJ dislocation is unknown.

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Elaphostrongylus rangiferi is a very common parasite in Scandinavian reindeer, causing losses due to cerebral nematodiasis and granulomatous parasitic pneumonias and also causing a discard of parts of the carcass at meat inspection. A more clear understanding is needed of the basic mechanisms whereby these effects (both beneficial and detrimental) are exerted.

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However, some possible exceptions were detected and these findings are discussed in relation to their influence on segregation distortion patterns. The analysis is an extension to the three approaches, which increases the performance for one of the three approaches. Also, the importance of a careful characterization of the skin lesion is stressed.

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The serum half-life of the antibody was approximately 10 h at doses of 0.1 to 7.5 mg/kg and approximately 18 h at a dose of 15 mg/kg. Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. A Large Scale Biorational Approach Using Bacillus thuringiensis israeliensis (Strain AM65-52) for Managing Aedes aegypti Populations to Prevent Dengue, Chikungunya and Zika Transmission.

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We aimed to test this hypothesis using previously unpublished data from eight European, Canadian, and US case-control studies of the International Lymphoma Epidemiology Consortium (InterLymph). Three substrates have been employed for the kinetic analysis of the enzyme, Histone III-S, FKKSFKL-NH2 (analogous of the pseudo-substrate of the enzyme) and MBP4-14 (part of basic myelin protein) protein. The effect of temperature on motility and survival of ejaculated human spermatozoa was investigated with the aid of the multiple exposure photography (MEP) method for objective sperm motility determination. One hundred and fifty-two consecutive patients were evaluated radiologically with water-soluble radio-opaque contrast enema before surgery for closure of the protective colostomy. Application of our dyadic validation criterion indicated that the full DCS cannot be considered a dyadic measure.

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coli in a complex medium, milk diluent, is also reported for both off-chip and on-chip assays. On the contrary, treatment with a PEG-LAA modified LNC carrier reduced the growth of the tumor volume, which did not exceed 1000 mm(3) by day 25.

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TREATMENT OF SEVERE INFECTED CORNEAL ULCERS BY SUBCONJUNCTIVAL INJECTIONS OF PENICILLIN TWICE DAILY WITHOUT HOSPITALIZATION, WITH SHORT REVIEW OF OTHER METHODS. HC implants showed a statistically significant higher mean crestal bone loss when compared with HS implants at year 10.

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Actinic reticuloid: action spectra and UVA protection factor sunscreens. Impact of renal function deterioration on adverse events during anticoagulation therapy using non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation. The importance of endosomal acidification in alpha(v)beta6-mediated infection was confirmed by experiments showing that infection could be blocked by concanamycin A, a specific inhibitor of the vacuolar ATPase.

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Protected mealtimes is a British concept that changes the organizational structure of mealtimes and provides a focus on the mealtime by ceasing all non-acute activities while patients are eating. Pneumoperitoneum in the Setting of Pneumatosis Intestinalis in Children: Is Surgery Always Indicated? Patients with myocardial infarction (MI) often report lower health-related quality of life (HRQoL) than those without MI. Here we show that these conductivity changes do not appear if the purple membrane is immobilized.

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We have investigated the evolutionary history of the 4q35 paralogous region, and of a sub-family of interspersed LSau repeats. Accurate diagnosis of respiratory disease depends on understanding noises. Five cases illustrate a spectrum of family psychopathology and resultant childhood suicidal tendencies.

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Substantial investments in promoting breastfeeding have taken place in the past 10 years in Scotland. Pyrazolo derivatives as potent adenosine receptor antagonists: an overview on the structure-activity relationships. An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo.

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Our study shows that the co-cultures of PBMCs separated from patient blood clots provide an additional source for JEV isolation. Key clinical insights from the sudden cardiac death in heart failure trial. The anthropology of psychopharmacology: commentary on contributions to the analysis of pharmaceutical self and imaginary. Because Phx is a phenoxazine derivative like actinomycin D, we examined its effects on the proliferation of the human leukemia cell lines K562, HL-60, and HAL-01.

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Electrophysiological actions of cyclosporin A and tacrolimus on rat hippocampal CA1 pyramidal neurons. Consideration of the barriers to clozapine therapy will be important to its use and to its continued success in an outpatient setting. Nutrition, inflammation, and leptin levels in aging and frailty. Brain injury, handedness, and speech lateralization in a series of amobarbital studies.

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The technique stems from interactions of laser light with moving particles. The endpoint for successful block using the nerve stimulator has been described by previous authors as a bicep motor response (twitch) and recently by a deltoid motor response. The SLR-based LFA pulse sequence was used to maximize the inorganic phosphate signal in a phantom, after which volunteer metabolite signals were selectively maximized and compared to their correlates acquired with conventional spin-echo methods. PrEP can be cost-saving if delivered to individuals at increased risk of infection. Intestinal flora is required to develop a normal adaptive immune response in the periphery.

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In the present study, cytochrome c (cyt c) was used as a model autoantigen to investigate how self-proteins are involved in the priming of autoimmune T cell responses. Pierre Pouget PhD, Nicolas Wattiez MSc and Antoni Valero-Cabre MDPhD.

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A comparison of estrogen use by women with endometrial cancer, gynecologic disorders, and other illnesses. A total of 30 Morse Cone conical tapered implants (10 implants per group) were used in this study. It is postulated that the redistribution of drug from the lysosomal compartment to organellar membranes is the critical event which triggers the irreversible injury cascade.

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The global results demonstrate that the plasmid does not play a significant role in surface colonization because (i) CECT4999 and CT218 were equally chemoattracted towards and adherent to eel mucus and gills, and (ii) CT218 persisted in gills from bath-infected eels 2 weeks post infection. DNA sequencing of temporal artery biopsy specimens from GCA cases, in comparison with non-GCA controls, showed no evidence of previously identified candidate GCA pathogens.

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The J-bone graft for anatomical glenoid reconstruction in recurrent posttraumatic anterior shoulder dislocation. The results were related to the lecithin sphingomyelin (L:S) ratio.

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Here, we demonstrate that stimulation of Rat-2 or embryonic stem cells with activators of ERK1/2 or of cAMP-dependent protein kinase induced phosphorylation of endogenously expressed LKB1 at Ser(431). Effect of roentgen radiation on histones and DNA in rat bone marrow and liver nuclei Service Use in the Month and Year Prior to Suicide Among Adults Enrolled in Ohio Medicaid.

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Recordings of biological specimens demonstrate elimination of out-of-focus haze for densely packed foci and concomitant substantial improvement of contrast and resolution. Association of UBE2L3 polymorphisms with diffuse cutaneous systemic sclerosis in a Japanese population.

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The study demonstrated that a high proportion of the isolates was tolerant to antibiotics and/or heavy metals, highlighting the on-farm BPS enrichment in such genetic traits. Three round well-defined subcutaneous masses, approximately 1 cm in size, were present on the occipital, parietofrontal and right mastoid region, respectively. The role of cytokines in polymyositis: interferon-gamma induces class II and enhances class I major histocompatibility complex antigen expression on cultured human muscle cells.

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Kinetic Monte Carlo simulation of CO adsorption on sulfur-covered Pd(100). Gastrointestinal leiomyosarcoma metastatic to the liver is considered most resistant to any combination of systemic chemotherapy containing doxorubicin and/or ifosphamide.

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Low levels of ID2 expression in human GBM tissues may identify a clinical group in which metabolic targeting of glycolytic pathways can be expected to have the greatest therapeutic efficacy. Fluid collections and transposed ovaries--not always functional cysts. In this study, we used data from a cross-sectional survey on 2151 calves from 102 veal calf farms to identify potential risk factors, with the goal of reducing MRSA prevalence by developing intervention strategies. Examination of the kidney revealed a minimal-change glomerular lesion and moderate arterionephrosclerosis. A colloidal interpretation of biological stimulation and depression.

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There are several examples which show that the critical exponents can be dependent on the initial condition of the system. We then rigorously demonstrate that no phase separation in an athermal FP state of hard particle mixtures on a lattice is possible merely due to size disparity or nonadditivity, if the configurations are weakly correlated, i.e., are quasirandom. These findings should help researchers in Guatemala and similar LMIC to develop community-based interventions for NCD prevention in school-age children that are effective, feasible, and culturally acceptable. Systematic review: comparative effectiveness and harms of disease-modifying medications for rheumatoid arthritis. Growth factor-like effects mediated by muscarinic receptors in PC12M1 cells.

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Rapid induction of alkaline phosphatase activity by retinoic acid. MUAP amplitude was lower in constipated and incontinent patients with respect to healthy subjects.

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The study showed that the presence of five or six HLA MM was not a risk factor for graft survival after LDKT. Early extubation after surgical repair of congenital heart disease.

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All the mutant Env glycoproteins were expressed, processed and transported to the cell surface in an essentially wild-type manner. How Croatian Franciscan friars took care of their ill brethren in the 17th through the 19th century We describe a novel cooperation between a soluble component of the innate immune system, the mannose-binding lectin, and Toll-like receptor 2 that both specifies and amplifies the host response to Staphylococcus aureus. This paper describes the use of a flap which is the random portion of an island flap based on superficial temporal vessels. The null hypothesis tested was that there are no differences in the activities of dentinal MMPs before and after treatment with a one-step adhesive system.

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Precocious thymic involution manifest by epithelial injury in the acquired immune deficiency syndrome. Radiolabeling was carried out in a fast, reproducible, easy, and stable way with high radiochemical purity and did not interfere with epitope recognition. Retrospective review with a mean follow-up of 19 months (range, 1 to 56 months). A successful repair of concomitant rupture of the interventricular septum and left ventricular free wall after acute myocardial infarction

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We sought to quantify the prevalence and identify risk factors for early, undesired weaning that mothers attribute to physiologic difficulties with breastfeeding. Those requiring operative fixation are usually amenable to either K-wire, interfragmentary screw, or plate fixation. We believe that IOU should have a wider application and that surgeons and radiologists should develop cooperative working relations similar to those that exist for operative radiography. The need for a classification of problems observed in child psychiatry goes hand in hand with the desire to standardize diagnostics.

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Detection of foreign invaders is mediated by a class of receptors that are known as the pattern recognition receptors, such as the family of Toll-like receptors (TLRs). Acute renal failure was induced in rats 24 hours after dehydration by an intramuscular injection of glycerol. Evaluation of renal function in patients with cirrhosis: where are we now? Edema, cation content, and ATPase activity after middle cerebral artery occlusion in rats.