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Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion. Past studies of sepsis epidemiology did not address misclassification bias due to imperfect verification of sepsis detection methods to estimate the true prevalence. Crystalline composition of urinary stones in recurrent stone formers. The results obtained suggest a possibility of metaplastic transformation of the lung epithelium. The enigmatic kikuchi-fujimoto disease: a case report and review.

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Forty-three patients (25 men, 18 women) with mean age of 43.3 (range 15-68) years were included. Participant data responses to survey questions were collected from August 20, 2010, to October 3, 2010. Local density dependent potential for compressible mesoparticles. Micropercutaneous nephrolithotomy is a step forward towards the search for a less invasive kidney stone treatment.

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Effect of the level of iodine in the diet of pregnant ewes on the concentration of immunoglobulin G in the plasma of neonatal lambs following the consumption of colostrum. Despite advances in technology, its mortality rate has changed minimally over the past two decades, and new therapies are needed. The obesity epidemic and sugar-sweetened beverages: a taxing time. A total of 122 cigarette smokers (115 men and 7 women) and 14 hookah smokers (all men) with age ranging from 16-80 years were studied.

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Immunoprecipitation using this antiserum brings down two protein bands, a major band of 143 kDa and a less abundant, more diffuse, band of 158 kDa. Hypoplastic uterus: the importance of gynaecological ultrasound in its diagnosis--case report and review of the literature. The NO2 sensing test revealed that the sensor response was enhanced by decoration with Co nanoparticles.

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Before the treatment, the wall-adjoining cells were with high hyperplasia of intracytoplasmatic tubules, which pressed in separate groups-packets the numerous mitochondria with data about hyper-reactivity, on the background of scarce or absent tubulo-vesicular structures. A protein kinase C (PKC) agonist selective for the beta I isozyme, 12-deoxyphorbol 13-phenylacetate 20-acetate (dPPA), induced NF-kappa B-like binding activity and surface expression of E-selectin and VCAM-1 in human umbilical vein endothelial cells (HUVEC), similar to the effects of tumor necrosis factor-alpha (TNF-alpha). Determination of lactate, pyruvate and ammonia under ischemic conditions plus a pyruvate loading test were particularly useful.

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The demonstration of striking extracellular major basic protein in biopsy specimen implicates a role for eosinophils in the pathogenesis of this disease. Northern-blot and immunoblot analyses indicated higher MIPS expression and accumulation in immature seeds than in other soybean tissues.

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Teratogenicity of dimethoxyethyl phthalate and its metabolites methoxyethanol and methoxyacetic acid in the rat. A polyclonal cell-specific antiserum used to probe the cell surface was monitored by indirect immunofluorescence.

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Empirical evidence supports the hypothesis that use of EMA can improve the quality of AUD treatment research when compared with standard assessment methods because it provides more accurate reporting, allows investigators to examine the dynamic unfolding of the behavior change process at an individual level, and can be used to augment and improve clinical assessment and treatment. It was concluded that the beginning steps had been undertaken toward psychometric development of a reliable technique for the measurement of color preference. We used electrostatic force microscopy (EFM) to investigate local conducting states of atomically thin individual graphene oxide (GO) sheets and monitor the spatial evolution of their conducting properties during the reduction process. This generic tool can be used for drug delivery, electrotransfection as well as electrostimulation. To investigate their function, we deleted (delta) pheromone-precursor genes (delta ppg1, delta ppg2) and receptor genes (delta pre1, delta pre2) and generated single- as well as double-knockout strains.

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Specific care and management depend on the predominant alteration, the stage of HIV disease and the medical and antiretroviral history of the individual patient. Fifteen minutes later, a source-monitoring task was administered. Our study highlights the role of iron in modulating ferritin aggregation in vivo in the disease HF.

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Expression of these constructs was measured after targeted integration into three defined loci in murine erythroleukemia cells using recombinase-mediated cassette exchange. To report the spontaneous resolution of a traumatic macular hole that was considerably larger than in previously reported cases.

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New perspectives on the role of occupational therapists in an age of automation. With Kluyveromyces marxianus CBS 600, 26.5 g/l 2-PE and 6.1 g/l 2-PEAc in the organic phase were obtained, corresponding to space-time yields of 0.33 and 0.08 g/l h, respectively.

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The presence of 2 mM deoxycytidine (CdR) in growth medium substantially increased the deoxycytidine triphosphate (dCTP) and deoxythymidine triphosphate (dTTP) pools in a Chinese hamster ovary cell line, CHO-K1, and in a radiation-sensitive mutant, xrs-5, derived from it (Jeggo et al., 1982). One common characteristic of expanded-polyQ expression is the formation of intracellular aggregates (IAs).

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One major source of interlaboratory variability identified for TA102 appears to be the sensitivity of different types of automatic colony counter for detecting the micro-colony revertants that this strain produces. Apparent activation volumes for both the formation and decay of conducting states were positive and of comparable magnitude, namely, approximately 100 A3/event. This study aimed to investigate the relation between emotional intelligence and instable personality in substance abusers. Type II, thought to be immune-mediated, is rare, unpredictable and results in a severe fulminant hepatitis with a high mortality. The story is told of the Minneapolis demonstration which helped reduce infant mortality there from 81 to 65.

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The high-voltage pulses resulted in gene expression that was restricted to superficial skin layers and induced a local response. Sodium nitroprusside (SNP), a NO donor, reduced the viability of HDPCs in a dose- and time-dependent manner. Expression of a mutant regulatory subunit of cAMP-dependent protein kinase in the Caco-2 human colonic carcinoma cell line. Midkine inhibits inducible regulatory T cell differentiation by suppressing the development of tolerogenic dendritic cells. Genetic predisposition to sporadic cancer: how to handle major effects of minor genes?

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The influence of mutant lactobacilli on serum creatinine and urea nitrogen concentrations and renal pathology in 5/6 nephrectomized rats. Validation of a questionnaire for measurement of beliefs about the climacteric We present these cases and discuss the benign etiologies with emphasis on the role of surgery in both diagnosis and treatment. Transcriptome profiling identifies p53 as a key player during calreticulin deficiency: Implications in lipid accumulation. To reach these goals, daily intermittent or continuous forms of hemodialysis or hemofiltration are appropriate measures.

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However, symptom severity was much more strongly related to overall health status than the other measures. Electromyographic investigation indicated low amplitude signs, which were compatible with muscle disorder. Altretamine is a well tolerated oral agent with minimal toxicity. A Biocompatible Colorimetric Triphenylamine- Dicyanovinyl Conjugated Fluorescent Probe for Selective and Sensitive Detection of Cyanide Ion in Aqueous Media and Living Cells.

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This effect, however, was dependent on the copy number of enhancer repeats and was detectable in the presence of a single repeat. To investigate the effect of four variables: wavelength (633 nm and 780 nm), bandwidth filter (3 kHz, 15 kHz, 22 kHz), probe fibre separation (250 microns) and 500 microns) and distance of the probe from the gingival margin (2-3 mm and 4-5 mm) when assessing the vitality of anterior teeth with a laser Doppler flowmetry system. Anticancer effect of sirolimus in renal allograft recipients with de novo malignancies. The effect of synbiotic consumption on a battery of intermediate bio-markers for colon cancer was examined.

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Conversely, orientational reactions to emotionally neutral stimuli induced increases in the latent periods of evoked potentials. Here, we show that inhibition of AMPK in beta-cells by high glucose inversely correlates with activation of the mammalian Target of Rapamycin (mTOR) pathway, another cellular sensor for nutritional conditions. elegans Netrin gene unc-6 does not act in the same genetic pathways.

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Due to its better performance than traditional cryptography, Hao et al. We sought to assess the signaling relationship between EGFR and mutant K-ras, which is commonly detected in pancreatic cancer. We used general estimating equations to calculate the odds of school readiness in a nationally representative cohort of 4900 full-term and 950 late preterm infants. The results clearly show that the extent of adhesion to E-selectin and cell surface sialyl-Le(x) determinants is proportional to the amount of cell surface lamp-1.

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Gammagraphic localization of pheochromocytoma with (131I) meta-iodobencylguanidine Overall, these observations indicate a complex interplay between this viral protein and the host SUMOylation system. Five 2-wk old male calves were fitted with chronic catheters in the hepatic and portal veins and in the hepatic artery and with electromagnetic blood flow probes in the portal vein and in the hepatic artery. The rapid recognition of invading pathogen polysaccharides by host lectins might have a significant role in the outcome of the infection. The crystal structure of the mouse GITRL (mGITRL) was determined to 1.8-A resolution.

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Classification based on plasma cotinine levels showed a statistically significant (P less than 0.001) difference between smokers and non-smokers in liver homogenate ERDE activity. Anosmia and hyposmia have been observed in workers exposed to Ni- or Cd-containing dusts in alkaline battery factories, nickel refineries, and cadmium industries.

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Salbutamol and N6-ethyl carboxamidoadenosine, which activate adenylate cyclase, dibutyryl cyclic AMP (a cyclic AMP analogue) and forskolin did not augment EPO mRNA production, and no significant differences in the regression of log (EPO mRNA) on perfusate pO2, were found between experimental groups exposed to each of these compounds and controls. Comparative binding energy (COMBINE) analysis of influenza neuraminidase-inhibitor complexes. Hypercalcemia is one of the causes of J point and ST segment elevation, but the relationship has not been well studied. Either quantitative or qualitative modification of diet interferes markedly with the reproductive functions of the rat.

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Influence of Temperature, Relative Humidity, and Soil Properties on the Soil-Air Partitioning of Semivolatile Pesticides: Laboratory Measurements and Predictive Models. Affinity chromatography of human serum proteins using immobilized lectin from Allomyrina dichotoma. Spatial variation in migration processes and development: a Costa Rican example of conventional modeling augmented by the expansion method. Dimethyl disulfide could then be considered to be a characteristic compound of wild mussels.

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Here, we investigated the existence of IgE class anti-SSA antibodies (IgE anti-SSA antibody) and the relationship of such antibodies with foetal loss. Epidemiology of Chlamydia trachomatis using analysis of gene encoding of the major outer membrane protein Left ventricular systolic function is associated with sympathetic nervous activity and markers of inflammation in cirrhosis. We derive expressions for correction factors that can be used when the reduced scattering coefficients and the index of refraction are known. A preliminary assessment suggested that, notwithstanding the limitations and constraints involved, a worthwhile investigation aimed at validating the use of (137)Cs and (210)Pb(ex) measurements to estimate rates of soil loss from cultivated land could be undertaken.

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In the absence of Matrigel, cells in HEMA-MMA capsules were found to form aggregates in intracapsular pockets with central necrosis occurring at day 7 in large aggregates. Salivary flow has been recorded from conscious rabbits during 1 min periods whilst continuously chewing standard laboratory dry pellets or pieces of carrot and, in some animals, a mash of pellets with water. No significant increase in cytotoxicity to Me180 cell line was seen when rHuTNF was added to mitoxantrone.

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Personal BLAST Navigator (PLAN) is a versatile web platform that helps users to carry out various personalized pre- and post-BLAST tasks, including: (1) query and target sequence database management, (2) automated high-throughput BLAST searching, (3) indexing and searching of results, (4) filtering results online, (5) managing results of personal interest in favorite categories, (6) automated sequence annotation (such as NCBI NR and ontology-based annotation). Identification of the hemisphere activated by hemifield visual stimulation using a single equivalent dipole model. Is medical clearance necessary for pediatric psychiatric patients? The Mastectomy Reconstruction Outcomes Consortium is an 11 center, prospective cohort study collecting clinical and PROs following autologous and implant-based breast reconstruction.

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The mechanism of the injury did not predict functional outcomes. Although these measurable differences were detected in the pharmacokinetics of erythromycin, it is unlikely that a concomitant application of sodium butyrate with erythromycin or other CYP substrates will cause clinically significant feed-drug interaction in chickens. The dynamic interactions between the overall duration and recurring frequency of IH, the severity of IH, and the level of neural maturity at the time of IH will modify the ventilatory, metabolic, and cardiovascular responses to hypoxia. A stacked cohort cost analysis was performed on the US population from 1985 to 2013 to estimate the number of WDTC survivors in 2013. Non-vascularized and vascularized transplantation of epiphyseal plate autografts have been performed both clinically and experimentally for over 100 years.

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This prospective consecutive case study included 32 eyes diagnosed with POAG (19 with previous surgery and 13 without previous surgery, treated with topical antiglaucoma medication) and 12 eyes without signs of glaucoma. Angioedema, angiotensin converting enzyme inhibitors, and angiotensin receptor blocking drugs. Multiple sclerosis is a demyelinating disease frequently showing a relapsing-remitting disease course.

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Hemi-CCG methylation changes induced by hybridisation were recovered after genome doubling. Effect of colony-stimulating factors on the proteins synthesized by normal and leukemic myeloid progenitor cells.

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Analysis of the data observed indicated that myelosuppression could in some cases be attributed to direct infection of myeloid progenitors. 80 dogs with severe otitis externa that required total ear canal ablation with lateral bulla osteotomy. Outbreak of type E botulism associated with an uneviscerated, salt-cured fish product--New Jersey, 1992.

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Condensations products of thiosemicarbazide and thiosemicarbazones. Methodological and statistical aspects in perioperative chemotherapy trials. Besides characteristic clinical signs of ME, he also presented at cerebrospinal fluid analysis pleocytosis with lymphocyte predominance and class II cytomorphology, and delta and theta waves in the EEG.

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The effect of a purified glycoprotein excreted to the culture medium by Leishmania brasiliensis on the endocytic and degradative capacity of macrophages was studied. CD10 was strongly expressed in 14 out of 14 superficial BCCs and failed to express in 2 out of 2 deeply infiltrative BCCs. We investigated associations of breastfeeding (BF) durations and patterns and of timing of other dietary introductions with prevalence of asthma, wheeze, hay fever, rhinitis, pneumonia, and eczema among preschool children. Babies with low SVC flow had significantly lower MCA mean velocity and estimated diameter than babies with normal SVC flow.

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In this qualitative study ten semi-structured interviews with open-ended questions were carried out. Conclusively, these results could identify cytoplasmic p53 protein as a molecular switch that directly mediates the cytotoxic response of SAHA and thus open new therapeutic avenues.