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Rapid bioanalysis of vancomycin in serum and urine by high-performance liquid chromatography tandem mass spectrometry using on-line sample extraction and parallel analytical columns. Plasma parameters and anthropometric measures were obtained at baseline and at, early (24 h, 5 D) and late (6 months and 12 months) post-operative stages. This novel regulatory mechanism could have important pathophysiological implications for conditions in which alternations have been reported in AQP4 structure.

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For such drugs, new modes of delivery have to be developed for efficient and effective delivery of the drug to the target site. Reducing radiation-associated toxicity using online image guidance (IGRT) in prostate cancer patients undergoing dose-escalated radiation therapy. The apolipophorin-like group 14 allergens, despite their predicted hydrophobicity and lipid-binding activity, can induce high IgE responses and T cell stimulation. With these aims in mind, branched polymers are ideal candidates due to their unique rheological, mechanical, and biomedical properties derived from their structure, inaccessible for linear polymers.

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Effects of the mixture of Swertia pseudochinensis Hara and Silybum marianum Gaertn extracts on CCl(4)-induced liver injury in rats with non-alcoholic fatty liver disease In addition to the telomere shortening that occurs with cell division, oxidative stress can damage or shorten telomeres and induce a condition termed premature senescence, possibly before telomeres become critically short.

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Excellent original Chinese articles published at science citation index journals belong to the world and to China as well Effects of pectin and cellulose on fat absorption after massive small-bowel resection in weanling rats. Intermolecular interaction-induced hierarchical transformation in 1D nanohybrids: analysis of conformational changes by 2D correlation spectroscopy. Physicians need to consider the timing of the myomectomy, taking into account complications of pregnancy and infertility due to UF recurrence. One hundred and sixty three primary total hip replacement patients were recruited prospectively and randomised to one of four groups to receive a cemented femoral stem with either a matt or polished finish, and with or without a collar.

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Compared with late administration, early administration of ibandronate increased femur BMD in OVX rats and did not hinder bone fusion. Uptake of some radionuclides by woody plants growing in the rainforest of Western Ghats in India. However, it should not be used in patients with severe cholera, or in patients who are dehydrated and/or in whom renal function is impaired.

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Structure of an endo-beta-1,4-glucanase gene from Clostridium acetobutylicum P262 showing homology with endoglucanase genes from Bacillus spp. Since CST can be delivered by non-specialist healthcare workers, it has potential for use in low-resource environments, such as sub-Saharan Africa (SSA). Pulmonary functions in plastic factory workers: a preliminary study. The aim of the study was to systematically evaluate their efficacy of a combination therapy for SRS. Mice were conditioned with 300 cGy and received either RAPA at 3 mg/kg/day IP, CSA at 20 mg/kg/day IP, or no immunosuppression starting on the day before the transplant and continued for 4 weeks.

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If the binding constants are sufficiently high, macromolecular assemblies will form in a solution. Inhibition by salbutamol of GHRH-induced GH release in type 1 diabetes mellitus. Activation of cyclic AMP second messenger system stimulates secretion of beta-endorphin from fetal hypothalamic cells. Does health insurance mitigate inequities in non-communicable disease treatment? Their stings can cause different reactions, ranging from cutaneous, localized, and self-limited to serious systemic or fatal ones, depending on the envenoming species.

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We used a sandwich ELISA to quantitate a soluble form of endothelial leukocyte adhesion molecule-1 (sELAM) in serum. All of the cultures produced angiotensinogen, but cultures from 24 mo old rats produced significantly more (p less than 0.01). poliovirus vaccine stockpile remains an important resource that may potentially be needed in the future to respond to an outbreak if a live poliovirus gets imported into a subpopulation with low vaccination coverage.

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Among 167 patients who underwent open distal pancreatectomy, 62 patients whose age, gender, and pathology were similar to those of patients who underwent laparoscopic surgery were selected for this study. A significant correlation was found between RNHP and ENHP, both on the photographs and on the cephalograms.

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Cytogenetic evaluation of individual chromosomal radiosensitivity based on G(2)-assay has its perspectives in the formation of groups with increased risk of radiogenic cancer developing and its primary prophylactics among healthy population. The invasion and migration abilities of transfected HEC-1A cells were evaluated using Transwell assay and wound healing assay. This is particularly important for guides and workers, but also for visitors. The cross-over study also showed that the increased fibrinolytic activity during OC use is counterbalanced by an enhanced activity of thrombin-activatable fibrinolysis inhibitor (TAFI), a protein that participates in the inhibition of fibrinolysis.

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The antinutritional effects of dry beans, while minor, are of interest to nutrition professionals. Additionally, in vitro and in vivo studies suggest vitamin D favorably influences blood pressure and blood glucose control, strong risk factors for diabetic retinopathy. Difference in enzymatic properties between alpha-thrombin-staphylocoagulase complex and free alpha-thrombin. A case of an unusually large pseudomalignant spindle-cell proliferation (or inflammatory pseudotumor) of the urinary bladder in a young man is presented. Consequently, additional studies evaluated the protective effects of various natural and synthetic antioxidants, alone and in combination, with most studies focusing on alpha-tocopherol (vitamin E).

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Low-coherence fiber-optic sensor ring network based on a Mach-Zehnder interrogator. Compared to beta-CD, the inclusion ability of TM-beta-CD with PyTPP is stronger. Using visualisation as a catalyser for a collaborative approach integrating forensic data thus calls for better specifications. We found that clock genes were suppressed in B16 cells and tumors, but treatments inducing circadian rhythmicity, such as dexamethasone, forskolin and heat shock, triggered rhythmic clock and cell cycle gene expression, which resulted in fewer cells in S phase and more in G1 phase.

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Diagnosis of coronary artery disease by multigated radionuclide angiography during right atrial pacing. Adipocytes derived from PA6 cells reliably promote the differentiation of dopaminergic neurons from human embryonic stem cells. The total (active latent) activity of HMG-CoA reductase declined linearly with increasing cell density in cultures of three lines of mammalian cells. In cells receiving small interfering RNA targeting ACSL3, secretion of apolipoprotein B, the major protein component of VLDL, was inhibited and the lipoprotein was rapidly degraded.

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However, unresponsiveness to therapy and various complications may develop with disease progression. The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum.

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The relationship between surgical timing and hip fracture mortality is unknown in the context of developing countries where large delays to surgery are common. Epigenetic regulation of insulin-like growth factor signaling: A novel insight into the pathophysiology of neonatal pulmonary hypertension. Although it is likely that cardiovascular clinicians and scientists have the highest recognition of integrins in the cardiovascular system from drugs used to inhibit platelet aggregation, the focus of this article will be on the role of integrins specifically in the cardiac myocyte. Vulvodynia is a costly disease both economically and on its negative impact on patient quality of life.

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However, anticoagulant and/or antiplatelet agents use associated with PSAs required further intervention after failing observation-only management. This conclusion is supported by the findings that serum creatinine and kidney injury molecule-1 (Kim-1) gene expression remain elevated compared to young controls at 10 days post-injury. A Markov model was constructed to analyze outcomes including the number of deaths and cancers after a 3-year follow-up period or time horizon. ET-1 (10-100 nM) alone augmented cell proliferation, and was additive to the effect of EGF (0.48 nM) in a concentration-dependent manner.

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The histopathology of advanced chronic alcoholic pancreatitis is dominated by cellular degeneration, atrophy and fibrosis. Elevated plasma phospholipid transfer protein activity is a determinant of carotid intima-media thickness in type 2 diabetes mellitus. Intracranial transplantation and survival of tuberomammillary histaminergic neurons. However, due to limited tissue availability, performing such analyses can be challenging.

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Disease activity (inflammation, pain, joint symptoms) is associated with greater fatigue. Here, we demonstrate that partial least-squares discriminant analysis (PLS-DA) models of calibration Raman spectra from cells in pure cultures can be used to identify the lineages of individual cells in more complex culture environments.

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Polyphenols were partially identified and were found to consist mainly of hydrolyzable tannins, gallic and tannic acid derivatives. A possible reaction mechanism for BPA degradation involving three main aromatic intermediates, identified by GC-MS analysis, was proposed. Both systems of Rotary ProTaperNiTi and manual NiTi files used in the present study, did not create completely clean root canals.

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Occurrence of N-phenylpropenoyl-L-amino acid amides in different herbal drugs and their influence on human keratinocytes, on human liver cells and on adhesion of Helicobacter pylori to the human stomach. Acute tubular necrosis, intrarenal infections, focal nephrocalcinosis, hydronephrosis, and neoplasms also may occur. During periods of tachycardia induced by atrial pacing in eight patients, moderate increments in dP/dt(max) and (dP/dt)/CPIP (common produced intraventricular pressure) and moderate reductions in left ventricular ejection time (LVET) and Q-S2 were demonstrated. This transformation proceeds through an unprecedented mechanism which exploits the reactivity of gold(I)-heteroatom bonds to form sulfinate anions.

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Reminder fatigue over time, with increasing numbers of reminders and with increasing complexity of patients, is not inevitable. Squamous-cell metaplasia with severe dysplasia of the colonic mucosa in ulcerative colitis. Forced reduction of DHX33 in these cancer cells abolished tumor formation in vivo Our study demonstrates for the first time that DHX33 acts as a direct transcriptional regulator to promote cell cycle progression and plays an important role in driving cell proliferation during both embryo development and tumorigenesis.

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Endogenous production of the anabolic hormones thyroxine, triiodothyronine and somatotropin was found to correlate with a high level of protein utilization in rats within the first days of life after birth. Body mass index and blood pressure in Korean men and women: the Korean National Blood Pressure Survey. The purpose of the current study was to examine the effects of acute administration of nicotine on specific measures of smooth pursuit eye movements and visual attention. To facilitate these studies, we have developed a procedure to isolate spinach photosystem II complexes with an antenna size of approximately 100-110 chlorophylls per reaction center. A mice study consisting in the follow up of the lungs at different stages of tumor development is then related.

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Central hypotensive effect of diprenorphine in normotensive rat and SHR. Effects of treatments by calcium and sex hormones on vertebral fracturing in osteoporosis.

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Thirty-two evaluable good risk patients with multiple myeloma received a 70-day tapering course of prednisone beginning at a dose of 1.2 mg/kg/day. In addition, the group velocity of this mode is close to the speed of light in the substrate, and its propagation length is tens of micrometers at the optical communication wavelength.

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The isolated pearly papules showed the typical findings of basal cell carcinoma. Randomly selected men and women hospitalised for AMI between 1999 and 2001. Changes in the sorptive properties of tissue in acute radiation injury The linear response kernel of conceptual DFT as a measure of aromaticity. Serum creatinine concentrations continued to rise after withdrawal of the drug, but steroid therapy was effective in normalizing renal function.

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Simultaneous determination of the quantity and isotopic ratios of uranium in individual micro-particles by isotope dilution thermal ionization mass spectrometry (ID-TIMS). We investigated the effects of biological variation in risk factors on risk estimate accuracy and whether current primary prevention screening (risk assessment) models correctly categorize patients. Our findings may contribute to insight in how clinicians respond to emotional concerns in follow-up consultations and have implications for communication skills training. PA change in adolescents is a complex issue that is not easily understood.

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The combination of extreme premature delivery before 28 weeks of gestation, severe idiopathic respiratory distress syndrome, and a resistance index of the middle cerebral arteries under the 5th percentile seems to be a risk factor for early neurological morbidity in fetuses with AREDFV. CT and MR scanning revealed that all patients except one had bilateral multiple intraparotid cysts.

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These results confirm an essential role for TNAP in craniofacial skeletal development and demonstrate the efficacy of early postnatal mineral-targeted enzyme replacement for preventing craniofacial abnormalities including craniosynostosis in murine infantile HPP. Experimental and epidemiological studies have shown that higher intake of n-3 long-chain polyunsaturated fatty acids may decrease the risk of various diseases such as diabetes. The risk of asthma symptoms related to biomass smoke exposure appears to differ by sex. Patients in each subgroup showed signs of a characteristic personality. Specific and selective targeting of hypoxic tumor areas can be achieved at all three steps of a gene therapy treatment: delivery of the therapeutic gene to the tumor, regulation of gene expression, and therapeutic efficacy.

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The diagnosis is established by history, physical examination, and functional venous testing with duplex imaging or phlebography. Six principles developed for the effective use of science advice in making regulatory decision have been adapted and are proposed with accompanying guidelines as a framework for the development of a science-based decision making process to facilitate the implementation of the 3Rs by governmental regulators.

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The ranking by DMFT index scores was lower for developed countries than for developing countries. Mislocalization of oskar RNA to the anterior pole, which has been shown to result in induction of germ cells at the anterior, leads to anterior protection of maternal Hsp83 RNA. atratus fat body, help us to better understand the SK signaling pathways and its physiological role in insect biology.

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Rejection in lung transplantation--an immunohistochemical study of transbronchial biopsies. Fewer studies employed IPT, however this approach appears promising. CLL patients are at a significantly increased risk of developing a second malignant neoplasm. The neuroprotective effects of orthosteric agonists of group II and III mGluRs in primary neuronal cell cultures are dependent on developmental stage. Patients had identifiable meanings for their illness, and these may be associated with their response to renal disease.

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THE LIMITED EFFECT OF COINCIDENT ORIENTATION ON THE CHOICE OF INTRINSIC AXIS (.). One hundred and ninety-four consecutive fetuses from singleton pregnancies undergoing chorionic villi sampling (CVS) were evaluated by transabdominal ultrasound. Simplified Thresholds for Pediatric (Pre)hypertension: One Approach to Improve Recognition and Outcome. Previous work shows that immune function may be traded off with other fitness components such as reproduction. Here we performed a meta- analysis to evaluate the impact of PHT on the results of hepatectomy for hepatocellular carcinoma (HCC).

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Demographic, clinical, and radiographic data were available for 61 patients with OPSCC, treated in 2004 to 2012 at a single tertiary academic referral center, with at least one baseline and one posttreatment PET/CT. Qualitatively similar results were obtained for both reversible effects and irreversible (i.e., sustained) effects. The delineation results we obtained are very encouraging and show the interest of the proposed framework.

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Neurological and neurocognitive functions from intrauterine methylmercury exposure. There was no difference regarding postoperative complications and knee function.