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Proscalpin (Finasteride)

Proscalpin works by inhibiting type II 5-alpha reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT). This converted form of testosterone stimulates development of the penis, testes and scrotum, as well as other male sexual characteristics such as body hair and pubic hair. DHT also promotes growth of the prostate. In 1992, Proscalpin 5 mg per day was approved by the U.S. Food and Drug Administration (FDA) as a treatment for benign prostatic hyperplasia. The agent was marketed by Merck under the name Proscalpin. Patients need to allow at least 6 months for the therapeutic effects to be determined. Symptoms that may improve include difficulty urinating, increased urination frequency and decreased urinary flow. If the therapy is discontinued, symptoms will return within around 6 to 8 months. In 1997, Proscalpin 1 mg per day was approved by the FDA as a treatment for male pattern baldness and this time the agent was market by Merck as Proscalpin. Proscalpin 1 mg per day was shown to benefit men with mild to moderate hair loss in a five-year study. Two thirds of the men who took the medication on a daily basis saw some regrowth of their hair, while those who did not take the medication experienced further hair loss. Analysis showed that for all five years of the study, the average hair count remained above baseline among the Proscalpin group and was increased compared to those who did not take the treatment. The medication is only effective for as long as it is used, with the therapeutic effects being lost within 6 to 12 months after discontinuation of the therapy.

Other names for this medication:
Finasteride, Androfin, Avertex, Daric, Fenered, Finahair, Finalo, Finalop, Finar, Finara, Finast, Finax, Fincar, Finpecia, Firide, Monast, Prohair, Propecia, Proscalpin, Proscar, Prosteride, Reduprost, Renacidin, Sutrico, Symasteride, Tealep, Tensen,

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Finally the results of these tests of Normality must be shown to be free of sample size effects. Using the GFP/CCl4 model, we found that transplanted Liv8-negative cells efficiently repopulated into cirrhotic liver tissue and differentiated into albumin-producing hepatocytes under persistent liver damage induced by carbon tetrachloride. Ibotenic acid lesions of the ZI produced similar results, having an insignificant effect on locomotor activity stimulated by low dose amphetamine (1 mg/kg) and an attenuation of apomorphine-induced stereotypy which was of a magnitude comparable to that produced by DNQX. Having no insurance at the start of pregnancy was associated with significantly lower risk of teeth cleaning before pregnancy and both before and during pregnancy.

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The next step of the investigation was to define an appropriate constitutive framework and develop a procedure for identification of the constitutive parameters. We also hypothesized that bacterial diversity is affected by pesticides. Calcium ion influx in microglial cells: physiological and therapeutic significance. Inhibition of Malaria Infection in Transgenic Anopheline Mosquitoes Lacking Salivary Gland Cells. High-dose therapy and autologous stem-cell transplantation in angioimmunoblastic lymphoma: complete remission at transplantation is the major determinant of Outcome-Lymphoma Working Party of the European Group for Blood and Marrow Transplantation.

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In 1978-79 13 Assamese populations--two Muslim groups, five Mongoloid groups and 6 Hindu caste groups--have been investigated for the distribution of anthropometric, anthroposcopic and dermatoglyphic traits as well as for the distribution of ABO blood groups and PTC taste sensitivity. The Proline/Arginine Dipeptide from Hexanucleotide Repeat Expanded C9ORF72 Inhibits the Proteasome. A human pharmacological study comparing conventional heparin and a low molecular weight heparin fragment. The role of digital health technologies in management of pain in older people: An integrative review.

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Moreover, MTHFR TT genotype was independent risk factor of thick CIMT. Treatment of malignant pleural mesothelioma (MPM) remains disappointing, although recent reports suggest that multimodality therapy including surgery may provide a significant survival benefit.

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The aim of the present study was to describe the spectrum of liver disease in isolated infection by the human immunodeficiency virus and in the acquired immunodeficiency syndrome as well as evaluate whether clinical and/or biological data exist to permit specific diagnosis in liver biopsy. The sense fragments were C-terminally modified by addition of either a nuclear localization sequence (NLS) or a STOP codon to address the impact of their intracellular distribution. Epinephrine autoinjectors are commonly prescribed in the United States but are not readily available worldwide.

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Forefoot eczema (FE) is characterized by dry fissured dermatitis of the plantar surface of the feet. Global LAEP and HADS showed no significant group differences at baseline or changes over a 3-month period. Proteases, abundantly present at inflammatory foci, can degrade myelin.

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Anaplastic lymphoma kinase (ALK) inhibitors for second-line therapy of non-small cell lung cancer. To describe the incidence of TDR in Oklahoma and to examine whether TDR rates have increased with time.

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The hmd gene of histamine dehydrogenase from Nocardioides simplex was overexpressed in Escherichia coli, and the resulting enzyme was purified to homogeneity. A simple model incorporating the classical laminate theory and plate theory is presented to predict the deformed shape of the simply supported laminate plate. The structure of the layer formed after polymer adsorption onto a spherical particle is numerically studied by means of the application of the Single-Chain Mean-Field theory.

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The radionuclide studies provide information regarding structural change and physiologic derangement with a low radiation dose to the patient. Reproducibility of neuroimaging analyses across operating systems. Polymorphic Y chromosomes harbor cryptic variation with manifold functional consequences. Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts.

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Although many have been superseded by conventional pharmaceutical approaches, there is currently a resurgence in the interest in natural products by the general public and the use of complementary and alternative medicine is increasing rapidly in developed countries. As well, a comparison between this tumor and cholangiocarcinoma was made to determine whether these two types of liver cancers are closely related. For bone engineering, the optimal scaffolding material and composition has yet to be elucidated. The outcome is not always benign as fatal complications may occur. Sample stacking for the analysis of penicillins by microemulsion electrokinetic capillary chromatography.

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In addition, we found a number of task-related activation differences surrounding this core-network. These findings represent the first systematic dissection of the cytoplasmic domains required for Fra-mediated axon attraction in the context of full-length receptors in an intact organism and provide important insights into attractive axon guidance at the midline. Children with hemiplegic cerebral palsy participated in three experiments designed to examine interlimb coupling during reaching and pointing/grasping tasks. Plasma, kidneys, and livers from vehicle- and cisplatin-treated wild-type and Mrp2-null mice were collected for quantification of platinum and toxicity.

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These results suggest that, at least in part, the binding of PVR with DNAM-1 negatively regulates osteoclast formation. Based on these results, two relevant issues need to be addressed: understanding the relationship between haze and fine particles and understanding how to control PM2.5. These findings suggest that, in very preterm infants, perinatal neurological injuries could be associated with abnormal maturation of the autonomic nervous system. Despite the devastating effects of mutations in Zic2, the cellular and molecular mechanisms that provoke Zic2-deficiency phenotypes are yet unclear.

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We have analyzed cell surface-bound carbohydrates in two different model systems for metastasis composed of closely related tumor cell lines with differing metastatic potential. To inform future policy, planning, and management in the EMRP, we quantified and mapped ecosystem service values, assessed their spatial interactions, and evaluated the potential provision of ecosystem services under future land-use scenarios. Shouguang chicken and Silky chicken are both lowland chicken breeds.

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Stenosis of the aqueduct of Sylvius due to a sub-ependymal spongioblastoma: anatomoclinical study A brief review of the normal sensory innervation of teeth is presented, especially concerning the fibers that are immunoreactive (IR) for calcitonin gene-related peptide (CGRP). In placental diseases including preeclampsia and preterm birth, curcumin reduces pro-inflammatory cytokines. To investigate oral hygiene and periodontal status of 12- and 15-year old Greek adolescents, in relation to sociodemographic and behavioural parameters. Since 1977, when it was first demonstrated that a small number of patients with refractory leukemia could be cured by bone marrow transplantation, there has been an international effort to increase the proportion of patients cured.

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Average pachymetry of 1 central zone and 12 small zones around the center may be shown in the pachymetry map by simply formatting the system. Temporal lobe epilepsy (TLE) is the commonest type of epilepsy in adults, and the hippocampus is indicated to have a close relationship with TLE. Analysis of Ha-ras 1 allele frequencies in hereditary non-polyposis colorectal cancer. As a part of myocardial preservation, cardioplegia is the most important procedure since it influences significantly the ischemic metabolism of the heart during the operative time.

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The findings suggest that strategies for preparing patients (especially older patients) for continued self-care may need to be adjusted to the current short lengths of stay in the acute care hospital. Insights into the evolution of the antenna domains of Type-I and Type-II photosynthetic reaction centres through homology modelling.

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Tumor recurrence was defined as persistently elevated carcinoembryonic antigen levels, pathologic confirmation of endoscopic findings, or radiographically documented lesions in the liver, lung, or pelvis. From year to year, the number of WND cases varied widely, with major WND outbreaks in 1999, 2007, 2010, and 2012.

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Study of gelatin-agar intermolecular aggregates in the supernatant of its coacervate. Data were obtained from the NSW Midwives Data Collection (MDC), on 619,298 women who gave birth to a live, singleton infant at term (37-45 weeks gestation) from 1 January 1990 to 31 December 1997. Thus, non-specific loss of proteins from companion cells to sieve elements may explain the plethora of macromolecules identified in phloem sap.

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Samples were analyzed for levels of TNFi, interleukin (IL)-6, and soluble TNF-receptors 1 and -2 (sTNF-R1 and -2) and for presence of anti-TNFi Abs. NIH-CPSI was completed by each patient before and 6, 8, 16, 24 weeks after the treatment. Intramedullary compressive nail fixation for the treatment of severe Charcot deformity of the ankle and rear foot. On duodenoscopy, 1.0 x 0.6 cm sized active stage duodenal ulcer with oozing was observed at the posterior wall side below the pylorus. Further, mucosal immunization has been shown to induce both mucosal and systemic immunity to pathogens.

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Treatment of chronic myeloid leukemia with allogeneic bone marrow transplantation after preparation with BuCy2. On the plantar and palmar aspects of the feet and hand, dermatophytosis presents as an eczema-like chronic dermatosis.

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Linear regression analysis of velocity, cadence, stride length, gait cycle, and the ratio of contralateral to pathologic single limb support time as a function of postoperative time are reported with statistical error limits. Effect of hyperoxia on the cytoarchitecture of cultured endothelial cells. Factor Xa inhibitors were associated with a reduction in major bleeding events, but there was heterogeneity between the included studies, and the reduction was not statistically significant in a prespecified sensitivity analysis. This article presents the results of three surveys on NP prescribing practices from 1996 to 2001.

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In EggPC liposomes ubiquinol-10 induces a decrease in membrane water mobility near the probe, while in dimyristoyl liposomes a decrease in the membrane water content was found. All but one patient gave negative chlamydia cultures 10 days after the start of treatment, and all 65 patients gave negative results at the second examination seven days later. This paper summarizes the current situation of mental health services in the Arab world. Intraspinal tumors in infants and children: report of case and review of literature. However, cAMP increased norepinephrine secretion by a pathway distinct from that governing internal calcium levels, which correlates with habituation in the absence of elevated cAMP.

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Down-regulation of Cic by Mnb/Wap is necessary for promoting the growth of multiple organs, including the wings, eyes, and the brain, and for proper tissue patterning in the wing. Cohorts of patients in the UK, Netherlands and USA with 15,770 BSCC 60 degree heart valves were followed up to 18 years for the occurrence of OSF. Pollen grains with ellipsoid shape and rugulate ornamentation were dominant. Caution should, therefore, be exercised in extrapolating data on channel function obtained at room temperature to physiological temperatures.

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An overview of the infection of CMV, HSV 1/2 and EBV in Mexican patients with glioblastoma multiforme. Our data demonstrated that trastuzumab plus saracatinib was much more potent than either agent alone in reducing the phosphorylation of ErbB3 and AKT in both NCI-N87 and NCI-N87R gastric cancer cell lines.

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We conclude that spindle formation is the limiting microtubule function in these mutant cell lines at the nonpermissive temperature and that these cell lines will be of value for the study of the precise role of tubulin in mammalian spindle formation. Furthermore, there is an enrichment of keratin-positive cells from a heterogeneous population of L clones selected over serial migrations. Coordinated transcriptional and translational control in metabolic homeostasis in flies. Notably, circRNAs have been shown to serve as oncogenic stimuli or tumor suppressors in cancer.

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However, the mechanism of DEPTOR regulation with regard to rapid mTORC1 activation remains unknown. Cruciform samples were cycled to multiple strain levels while the perpendicular direction was held at a constant strain. The need for specialist training exposure in residency programs. The antagonism between strychnine and atropine may be explained taking into account the presynaptic action of atropine and the antagonism between strychnine and pentobarbital is in agreement with a GABAergic action of the barbiturates. The biological implications of these genetic differences are unclear and warrant further study.

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Rehabilitation positively influences return to activities and social roles in people with aphasia. The physical workload was classified as mild, with no need for ergonomic interventions.

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Avulsion fracture of the anterior superior iliac spine in a collegiate distance runner. A follow-up study of older adults with traumatic brain injury: taking into account decreasing length of stay.

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Effects of nano-selenium on antioxidant capacity and histopathology of Cyprinus carpio liver under fluoride stress The two variants--lobular carcinoma in situ (LCIS) and ductal carcinoma in situ (DCIS)--can be cured with conservation of the breast. Subsite mapping with 4-nitroanilides, chemical modification, and effect of possible cofactors. Antigenic differences between two strains of respiratory syncytial virus.

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Medication use by the quilombola population: a survey in Southwestern Bahia, Brazil GM3, a precursor for most of the more complex ganglioside species, is synthesized by GM3 synthase. The ability to control factors and also to monitor them using live cell imaging allowed us to develop quantitative assays that can be used to compare various drug candidates and also to understand the basic mechanism behind nerve regeneration after injury. Tibial plateau fractures were further analyzed depending on anatomical location: anterior-medial, anterior-lateral, posterior-lateral, and posterior-medial regions. The influence of thoron on instruments measuring radon activity concentration.

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The purpose of this review is to describe the basis for how ligand binding to TLR4 has the potential to cause renal dysfunction and the mechanisms by which this may take place in gram-negative sepsis. Common luminance measurement and calibration techniques are not applicable in the vicinity of MRI scanners. Radiation-induced morbidity evaluated by high-frequency ultrasound.

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The present study was undertaken to compare vasodilatations caused by substance P in retinal arterioles in vivo and in the extraocular retinal central arteries in vitro, and to analyze the mechanisms of its action. Random-effects meta-analysis was used to generate summary estimates. Muscle formation during embryogenesis of the polychaete Ophryotrocha diadema (Dorvilleidae) - new insights into annelid muscle patterns.

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Renal function should be monitored closely when sulfinpyrazone is prescribed, especially early after a myocardial infarction. CRA Doppler spectra and optic nerve sheath images were also obtained from healthy test subjects in an acute HDT experiment at 20 min of exposure (the ground-based analogue).

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We describe a case of Schilder disease in a young woman pointing out the most reliable diagnostic criteria for differentiating the disease from adrenoleukodystrophy. The logistic analysis of epidemiologic prospective studies: investigation by simulation.

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Comparing femoral version after intramedullary nailing performed by trauma-trained and non-trauma trained surgeons: is there a difference? The genu valgum deformity seen in the Ellis-van Creveld syndrome is one of the most severe angular deformities seen in any orthopaedic condition. Discriminating sex in South African blacks using patella dimensions. Epilepsy was an dalacin emulsion reviews for horrible bosses almost constant finding in our series, as was cognitive affectation. Recent studies show that there are tissue type-specific variations in their expression.

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An antibacterial ortho-quinone diterpenoid and its derivatives from Caryopteris mongolica. The proton NMR spectrum provided 255 resolved resonances that report how the explorer molecule local concentration varies with position on the surface. Development of an evidence-based protocol for care of pilonidal sinus wounds healing by secondary intent using a modified Reactive Delphi procedure. In addition, BAL from proxime tablet pc CF patients significantly impaired macrophage phagocytotic function, and this impairment was attenuated by HMGB1-neutralizing antibodies.

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High-quality evidence for the evaluation and management of calciphylaxis is lacking at this time due to its rare incidence and poorly understood pathogenesis and the relative paucity of collaborative research efforts. Placental proteins (human chorionic gonadotropin, human placental lactogen, pregnancy-specific beta 1-glycoprotein, and placental protein 5) in seminal plasma of normal men and patients with infertility. A retrospective review of the treatment of LTBI among kidney and/or liver transplant candidates was conducted to assess factors impacting therapy initiation, tolerability, and completion of therapy. A series of patients showing a previously unrecognized type of sliding hiatus hernia is presented and analyzed. Further prospective and comparative trials are required to determine whether NBI will cervista vs digene hpv play a role in evaluating and treating urothelial tumors in individual patients.

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Family-wide survey of miR169s and NF-YAs and their expression profiles response tagremin vs biseptol 480 to abiotic stress in maize roots. Comparison of Prompting Hierarchies on the Acquisition of Leisure and Vocational Skills. Characterization of host microbial interactions typically occurs on the cellular or protein level.

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Three reviewers watched all 10 episodes of the first season and coded incidents of substance use according to the substance used (alcohol, tobacco, or drugs), the way use was portrayed (visually or verbally), the source of the message (the character in the show involved in the incident), and the slant of the incident (endorsement or rejection). The deleterious effect of missing or spurious peaks and the dependence on match tolerances is also explored. Instead does nexium deplete magnesium levels of creating controls to handle the intricate dynamics of these robots, we can simply evolve the controls using a simulation to provide an evaluation function. Platelet adhesion was much more frequent and extensive than expected in biopsy 1.

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Directed Neural Stem Cell Differentiation with a Functionalized Graphene Oxide Nanocomposite. Immediate reactions following challenge-tests in children with atopic dermatitis. I further demonstrate how all these elements may be integrated into a unified architecture to generate behavior and autonomous learning. Characterization of the binding ketazol 200mg to ml surface of the translocated intimin receptor, an essential protein for EPEC and EHEC cell adhesion.

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Furthermore, the positive invariant sets, globally attractive sets and globally exponentially attractive sets are figured out as well. To determine the therapeutic effect of lisuride maleate on premenstrual mastalgia in premenopausal women. Acute infection is known to perturb psycho-neuroendocrine-immune (PNI) gene expression. The examination anxiron 5 mg tabletta norvasc was carried out in 10 healthy volunteers of both sexes, of the average age of 32.5 years, of the average weight of 77.4 kg. Generation and Characterization of Knock-in Mouse Models Expressing Versions of Huntingtin with Either an N17 or a Combined PolyQ and Proline-Rich Region Deletion.

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The treatment of transnasal endoscopic surgery for cerebrospinal rhinorrhea caused by transsphenoidal cephalocele is a feasible, mini-wound and safe approach. Five databases encompassing medical and social sciences were systematically searched using predefined search terms linked with breast cancer presentation and diagnosis and sub Saharan Africa. We conducted a systematic review and aimed to answer the following clinical question: What treatments improve outcomes in women with unruptured tubal ectopic pregnancy? Another group of highly homologous sequences is found which can be referred to as zinc-detoxifying P1-type ATPases with the metal binding pattern DCXXC in the venlift od 75 mg preconception N terminus.

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Nerve regeneration in a bony bed: vascularized versus nonvascularized nerve grafts. Assessing the Need of Discourse-Level Analysis in Identifying Evidence of Drug-Disease Relations in panklav forte cena Scientific Literature.

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Cross-sectional data were collected (2008-2009) from 1538 employed young adult participants in Project EAT (Eating and Activity among Teens and Young Adults), a diverse population-based sample. The amino acid sequence and structure of a uterotonic polypeptide extracted from the African plant Oldenlandia affinis DC have been determined. In addition, allografts lacking iNKT cells grafted into iNKT-deficient recipients result in more severe inflammation than ribavirin dosage genotype 2a/2c when grafted into WT recipients, while there was no significant difference with respect to induction of tolerance and graft survival. The target population, the assessments, and the management of the trial are described in detail. An automated microscopy-based screen of a kinase inhibitor library implicated an additional protective role for the PI3K/AKT/FOXO pathway.

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To adapt to Portuguese, of Portugal, the Depression, Anxiety and Stress Scales, a 21-item short scale (DASS 21), designed inh paediatric dose of augmentin to measure depression, anxiety and stress. To investigate the effect of inhibiting high mobility group box-1 (HMGB1) gene expression on the invasion and migration of endometrial carcinoma HEC-1A cells by small hairpin RNA. Neoaortic root dilatation, which is present in most patients and progresses over time, is strongly associated with significant neoaortic valve regurgitation. The authors studied clinical characteristics in 11 patients with intractable focal epilepsy and preictal headache (PIHA) using a standardized interview. Adopting extensive molecular dynamics simulations of a peptide helix, a five-dimensional model is constructed that successfully forecasts the complex structural dynamics of the system.