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Talopam (Topiramate)

Talopam is a sulfamate-substituted monosaccharide with anticonvulsant property. Although the mechanism of action has not been fully elucidated, Talopam antagonizes kainate/AMPA subtype of the glutamate receptors, which are ligand-activated cation channels that mediate the fast component of excitatory postsynaptic currents in neurons of the central nervous system. This antagonistic action results in stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing propagation of synaptic impulses, thereby impedes seizure occurrences. In addition, this agent augments gamma-aminobenzoic acid (GABA) activity and thereby attenuating GABAnergic inhibitory transmission.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Iatrogenic injuries of the peripheral nerves: analysis of 226 cases Using a neck or thorax CT, or a PET-CT distant metastases can be documented and a second tumour excluded. This study demonstrated that the CROM is a reliable device for measuring cervical relocation between different testers. This paper presents a detailed review on the sensor architectures, algorithmic techniques and applications which have been developed by Spanish researchers in order to implement these mono-sensor and multi-sensor controllers which combine several sensors. Nonempirical statistical theory for atomic evaporation from nonrigid clusters: applications to the absolute rate constant and kinetic energy release.

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In the urethra neuropeptide, and vasoactive intestinal polypeptide positive nerves were found in the muscular layer, calcitonin gene-related peptide, galanin and PHI nerves were localized in the epithelium. Recombinant lentivirus-delivered short hairpin RNAs targeted to conserved coxsackievirus sequences protect against viral myocarditis and improve survival rate in an animal model.

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This study showed that the number of hydrogen-bond acceptors of the analyte of interest may influence the recoveries in dried blood spot analysis and is a relevant factor to be investigated during method development and validation. Poisoning by the hallucinogenic mushroom hikageshibiretake (Psilocybe argentipes)--with special reference to subjective experiences during psilocybin poisoning The 5-HT3 receptor antagonist ondansetron (IV 10 micrograms kg-1 min-1 over 15 min) and the peripheral 5-HT2 receptor antagonist xylamidine (IV 100 micrograms kg-1 min-1 over 10 min) failed to modify food intake. Primary health care reform and implications for the organizational culture of Health Center Groups in Portugal

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Currently, there are no FDA-approved therapies to address this defect. In this study we characterize the growth and differentiation of hepatic stem cells utilizing embryonic liver cultures.

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We use a multipass optical cell to perform the first precision measurements of NSOR signals for a range of organic liquids and find clear distinction between proton signals for different compounds, in agreement with our earlier theoretical predictions. Cooperation of Musashi-2, Numb, MDM2, and P53 in drug resistance and malignant biology of pancreatic cancer. This study was conducted to explore the pattern of Internet use at the workplace and its dysfunctions. Laparoscopic repair of incarcerated low spigelian hernia with transperitoneal PTFE DualMesh. Obstetrics and the general practitioner: an account of the maternity work of a rural general practice in a cottage hospital.

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Similar lesions of the spinal trigeminal nucleus do not effect pattern formation in the ventral posterior nucleus. Angiogenesis inhibition has been shown to enhance the therapeutic efficacy of cytotoxic chemotherapy in colorectal cancer. Total gastrectomy was performed 10 years later and pathological examination of the specimen still revealed only intramucosal carcinoma.

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Bindability and digestibility of high-pressure-treated starch with glucoamylases from Rhizopus sp. LNG-IUS following an endometrial biopsy is an effective treatment for menorrhagia due to benign causes and could be an alternative to other forms of medical and surgical treatments. The choleretic action of sodium tyropanoate (bilopaque sodium) in the dog: preliminary observation.

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In this study, we described the cloning and characterization of an NRE-binding protein (NREBP) through expression cloning. arrhythmias and fibrillation, were recognized in the curves, and confirmed by comparison with synchronously recorded ECG data. Support for previously identified alcoholism susceptibility Loci in a cohort selected for smoking behavior.

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coli rfaD shows many similar structural features such as the ADP-binding beta alpha beta fold at the N terminus, as well as a high degree of homology of both the nucleotide and amino-acid sequences. Moreover, we demonstrate here numerically that this approach can be easily used to design an electrically pumped cw or pulsed spaser.

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Among these findings, tram-tracking of the optic nerve sheath complex is rare. Synthesis of pyridine-2-aldoxime-C-14 methiodide (2-PAM-C-14 iodide).

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We also discuss how additional assumptions can be incorporated into the same analysis to allow broader application of the technique beyond the specific example presented. The goal of the course is to present colposcopic cases that are unusual or instructive in terms of appearance, presentation, or management or that demonstrate new and important knowledge in the area of colposcopy or pathology. Effects of Nigella sativa oil and ascorbic acid against oxytetracycline-induced hepato-renal toxicity in rabbits. Altered expression of the prion gene in rat astrocyte and neuron cultures treated with prion peptide 106-126. The e.r.g.s were identical for all luminance settings of the unmodulated checks, suggesting that luminance rather than contrast determines the response.

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Severity state specific costs were used and defined by Clinical Dementia Rating scale. The direct band gap of BNNTs was determined at 5.38 eV, independent of the nanotube size and isotope substitution, by cathodoluminescences (CL) spectra. A 70-year-old male presenting with abdominal pain was clinically diagnosed to have chronic intestinal obstruction due to lesion in ileo-cecal junction based on barium meal follow through.

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Metatarsophalangeal joint dislocations of lesser toes are often seen in the setting of severe claw toes. The influence of chronic stress on anxiety-like behavior and cognitive function in different human GFAP-ApoE transgenic adult male mice. It has been adapted in some countries, considering the local dietary habits.

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In contrast, the suppressive subunits are tuned to orientations 45 degrees -90 degrees different from the excitatory subunits, which may underlie cross-orientation suppression. Comparative in-vitro activity of azithromycin, macrolides (erythromycin, clarithromycin and spiramycin) and streptogramin RP 59500 against oral organisms. In addition to mixed lymphocyte reaction (MLR) inhibition, chenodeoxycholate (CDC) inhibit ConA-induced IL2 production without any effect on IL2 R expression. It is concluded that the study of cross-language differences is important for the development of reading models that are generalizable across readers of different scripts.

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These results support the concept that the porcine CL is autonomous for much of its lifespan. Changes of electroretinogram without improvement of retinal circulation after radial optic neurotomy for central retinal vein occlusion. Cell-based biosensors for single cell monitoring and drug analysis. A cross-sectional study was performed from July 2013 to December 2013. Hippocampal population discharges such as sharp waves, epileptiform firing, and GDPs recur at long and variable intervals.

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Separation by high-performance liquid chromatography of two types of subunit from horse spleen ferritin. Physical examination and computed tomography were performed in all patients to access incidence of complications and degree of bone tissueconsolidation respectively in postoperative period. Reasons for discontinuing hashish use in a group of Central European athletes.

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Characteristic inclusions were observed in Schwann cells and macrophages of the twitcher mouse on the 5th postnatal day. Abnormalities of pulmonary vascular dynamics and inflammation in early progressive systemic sclerosis. The phosphorylated peptide, at nanomolar concentrations, is taken up by MCF-7 and LNCaP cells derived from human mammary and prostate cancers, respectively.

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The animals were sacrificed 2 or 3 days after antigen injection. The authors present the case of a 48-year-old female known to have malignant thymoma with metastases for 6 years and treated continuously for 4 years by corticosteroids with marked regression of tumor. Plasma TF and TFPI levels of our patients with hemangiomas were not different from healthy children and they did not show any significant difference in proliferative and regressive stages.

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Molecular genetics of supratentorial primitive neuroectodermal tumors and pineoblastoma. It was found in the experiments in vivo and in vitro that the contact of perfluorocarbon emulsion stabilized with proxanol 268 with blood plasma leads to the sorption of various plasma proteins on the surface of emulsion particles. Activation of mitochondrial biogenesis by heme oxygenase-1-mediated NF-E2-related factor-2 induction rescues mice from lethal Staphylococcus aureus sepsis.

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Modal DNA values of normal and malignant urothelial cells of the bladder in relation to nuclear size. Solitons for the rotating reduced Maxwell-Bloch equations with anisotropy.

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A total of 135 patients with myocardial infarction of different localization have been studied by the accepted ECG and the method of integral cardiotopography (ICTG). It is suggested that the paucity of myenteric ganglia and neurones in the regions examined is instrumental in causing the lethal condition described above. The use of nanocrystal quantum dot as fluorophore reporters in molecular beacon-based assays. Our objective was to examine whether rates of appropriate cardiac catheterization after admission for acute myocardial infarction varied between states with and without CON regulation of cardiac catheterization.

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Influence of measurement position on calculating pear tree stem sap flow Finally, Prmt1 did not modify the substrates of other methyltransferases from cells treated with methyltransferase inhibitors. Persistence of novel human parvovirus PARV4 in liver tissue of adults. The development of the adverse outcome pathway (AOP) and associated alternative in vitro assays have reshaped the assessment of skin sensitizers.

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Due to the complex management issues involved, these tumours are best managed in a tertiary referral setting. For heart failure (two RCTs), there was very low evidence for no effect on mortality, and low evidence for increased exercise capacity, and for no effect on health-related quality of life. In marked contrast, little regulatory effect of IL-4 produced by Valpha14 NKT cells on Th2 cell differentiation is suggested. Coupled reaction of creatine kinase and myosin A-adenosine triphosphatase.

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Since the olfactory system is known as a source of various migrating neuronal cells, we studied Reelin expression in the two chemosensory olfactory systems, main and accessory, during early developmental stages of human foetuses/embryos from Carnegie Stage (CS) 15 to gestational week (GW) 14. The Medicare Part D prescription benefit resulted in modest increases in average drug utilization and decreases in average out-of-pocket expenditures among Part D beneficiaries. Furthermore, it was observed that antibacterial properties of cadmium oxide nanoparticles on activity and growth of Staphylococcus aureus was more effective than Pseudomonas aeruginosa.

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And they can accumulate in the organs rich in RES in the body by passive targeting. Imaging electrically evoked micromechanical motion within the organ of corti of the excised gerbil cochlea. Here, we report a genome-wide analysis of maize that identified 147 Family-1 glycosyltransferases based on their conserved PSPG motifs. This under-recovery will significantly affect the diagnosis of adrenal insufficiency in critically ill patients with low albumin concentrations. To compare patient-matched instrumentation (PMI) with conventional total knee arthroplasty (TKA) in terms of limb alignment and component position.

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Double anomalous coronary origin from the pulmonary artery: successful surgical correction in an infant. Although the presence of a foreign body in the cranium after a head injury is a well-known entity, cases of retained intracranial foreign bodies causing a delayed onset of neurological symptoms are rare. Appendiceal abscesses can be effectively drained percutaneously using ultrasound-guided drainage under local anaesthesia, without complications. Three genome-wide scans for the loci that regulate plasma adiponectin concentration suggest further exploration on chromosomes 5, 9, 14, 15, and 18 is required.

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To delineate factors that may predict eventual urinary continence after bladder neck reconstruction (BNR) in the bladder exstrophy population. Arid zone rivers have highly variable flow rates, and flood control projects are needed to protect adjacent property from flood damage. Ventilatory responses to prolonged exercise with heavy load carriage. However, the size of individual SNB neurons is increased in the presence of androgen in either sex. Interpositional surgical repair models with these materials were significantly stronger than direct tendon-to-bone model repairs.

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Characterization of the bronchial epithelial cell cultures was assessed on the basis of cell morphology, cytokeratin expression, and ciliary activity. The efficiency of trapping mixed disulfides in vivo has been found to be higher for MMTS than for the more commonly used N-ethylmaleimide. Elucidation of these pathways using polyomavirus transforming proteins as tools is critically important in understanding fundamental regulatory mechanisms and hence to develop effective therapeutic strategies against cancer.

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Verruca vulgaris is a common skin condition in general practice, which often resolves without treatment. The future of PC patients relies on a successful multidisciplinary collaboration between experienced physicians, which can lead to important advantages in all the phases and aspects of PC management. Coprostanol and epicoprostanol were the sterols in largest concentrations in fresh manure and lagoon sludge samples.

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Greater short-term power can be produced in standing position, presumably due to a greater force developed per revolution. However, these structural signals are unlikely forwarded from IF2-G2 to the C-terminal fMet-tRNA binding domain (IF2-C2) because the connected IF2-C1 and IF2-C2 modules show completely independent mobility, indicating that the bacterial interdomain connector lacks the rigidity that was found in the archaeal IF2 homolog aIF5B.

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In UC patients, preformed tissue IgA and IgA produced in vitro were significantly increased compared with controls. Waist to height ratio and elevated blood pressure among children in Taiwan. Screening for MDROs was performed at ICU admission and discharge.

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Average exercise intensity was associated with reduced risk independent of the number of MET-hours spent in physical activity. Both primary tumors were slightly atypical cytologically but neither case demonstrated features of carcinoma. Mycotic aneurysm as a result of severe salmonella infection in the adult intensive care unit: two case studies. Inability of human adipose tissue cells to differenciate between triiodothyronine (T3) and thyroxine (T4). We compared different stages of CR development, including pre-emergent (PE), juvenile (JU) and the mature (MA) stages.

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We performed a retrospective, nested case-control study comparing cases with PNSP meningitis with controls with PSSP meningitis obtained from the Immunization Monitoring Program, Active (IMPACT) cross-Canada surveillance study of invasive infections. Synergists are designed to enhance the adsorption of steric stabilizers to the particles. IS A POSTOPERATIVE DAY ONE EXAMINATION NEEDED AFTER UNCOMPLICATED VITREORETINAL SURGERY? Although treatment is highly efficacious, selection of molecular markers in reinfections could indicate a decreased sensitivity or tolerance of parasites to the current treatments and the baseline prevalence of molecular markers should be closely monitored. Computed tomographic images provide full anatomic detail of the bony structures of the elbow joint in dogs.

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In contrast, when their times of administration were separated by 2 hours, no evidence of a drug interaction was noted. Suppressive effect of tetrahydrocannabinol on specific T cell subpopulations in the thymus. Effect of opiates on gastroduodenal motility following surgical operation.

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In particular a stimulant action of azimexone on the pluripotent stem cells of mice not subjected to the injurious agents could also be demonstrated. Few published studies address overall skin rejuvenation in this group using long-pulse (LP) laser to target pigmentation and stimulate dermal remodeling. In order to make recent data more transparant and practical we designed a classification and flow-chart for the management of recurrent cervical cancer. In particular, it is uncertain, whether several DOFs can be controlled simultaneously and proportionally by exclusively calibrating the intended activation of single DOFs. Genetic, clinical and laboratory characteristics, body composition indices, liver fat content by magnetic resonance imaging (MRI), histopathological and immunofluorescence examinations of liver biopsies.

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As a consequence of severe damages of tendon and of long lasting regeneration, it was believed that even in case of incidental healing restoration of the original function could not be expected. Thus, all solvent fractions, except for the water layer, showed potent scavenging effects. Rotator cuff tears are the most common cause of shoulder disability in people older than 50years, and surgical intervention is usually required for restoring functioning. Classification of Exudative Age-Related Macular Degeneration With Pachyvessels on En Face Swept-Source Optical Coherence Tomography.

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Internet-based RCTs can fulfil all the criteria of the revised CONSORT statement and are an appropriate method for studying low-risk interventions. Relation of blood acetaldehyde level to clinical symptoms in the disulfiram-alcohol reaction. Although rare, clinical diagnosis of glomangiomas may be sufficient in typical cases, however in atypical cases, like the one discussed here, further evaluation is often necessary. The timing of toxicity did not coincide to the presence of elevated fecal coliforms.

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Anxiety disorder is associated with reduced family functioning and poorer quality of life for Chinese patients. omeprazole pensa 20 mg flashback friday Unusually large adrenal adenoma excreting unusually large amounts of androgen metabolites in urine. To construct a eukaryotic expression vector of human autophagy maker protein P62 labeled with myc tag, and detect its biological function. Participants were 56 consumers with borderline personality disorder (BPD) who were psychiatrically disabled participating in a larger feasibility trial of Dialectical Behavior Therapy- Accepting the Challenges of Exiting the System.

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Induction of neurotoxicity by organophosphate pesticide chlorpyrifos and modulating role of cow urine. parocen tablet pc We explored the impact of OSA in morbidly obese patients with MetS on adipokines, pro-inflammatory markers, endothelial dysfunction, and atherosclerosis markers.

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A series of bicyclic derivatives based on wmf schmorpfanne 28 cm baclofen withdrawal symptoms 5,5-diphenylhydantoin (DPH) and/or 5-arylidene-hydantoin skeletons (BZH) are discussed as potential anticonvulsants. Implicit learning of nonlocal musical rules: implicitly learning more than chunks.

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Taken together, our results indicated that MCP-1 modulates the differentiation of monocytes into DCs and may thereby inhibit Th1 cell development. Expression of ephrin B1 is also detected on radial glial cells, extending all the way to their pial endfeet, clindamicina 300 side effects and on neurons in the mantle/intermediate zone but not in the cortical plate. Impact of maternal thyroperoxidase status on fetal body and brain size. This robust and accessible approach offers a new design paradigm for the parallel optimization of active surface area and mass transport in porous metal electrodes.

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We generated a specific antibody against netrin-5 to investigate its expression pattern tebantin medicine for diarrhea in the rodent adult brain. The aim of review article is to discuss the possible signaling pathways of NO in regulating GJ during IPC. An immunoenzyme test (ELISA) for the detection of circulating class-IgA antibodies in human leptospirosis

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Carrying an Accu-Chek kit: the role of the nurse in education in diabetology Only one positive cat was reported to be showing clinical signs of renal disease. These studies suggest peptazol 40 mg a cosa serve la that IGF-1 may mediate growth in muscle in response to variety of stimuli by autocrine/paracrine action or in response to certain stimuli possibly by endocrine action. Depletion of hepatic glutathione in male rats by starvation caused a significant increase in microsomal glutathione S-transferase activity, which was not affected by acute ethanol pretreatment.

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Autism is a neurodevelopmental disorder for clomipramine for dogs overdose which a number of genetic, environmental, and nutritional causes have been proposed. We also discuss signalling mechanisms that have been implicated in cancer and consider how similar mechanisms may improve axonal regeneration in the optic nerve.

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Based on our findings, we discuss the potential implications for BoNT/A function. The antiretroviral activity pantoprazole vs omeprazole reflux still of the five different classes of lexitropsins is discussed in terms of their structural differences. Analysis of paired serum samples from 514 vaccinated children showed that effective immunization with this vaccine could be performed after but not before the age of 16 to 20 months.

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Characteristics and outcomes of elderly patients receiving transitional care. The key idea of LHR is to estimate the feature weights through local approximation rather than global measurement, which is typically used in existing methods. Low-molecular-weight heparins (LMWHs) are being preferred to unfractionated heparin (UFH) because of their superior convenience and a omeprazole drug interaction with diazepam valium comparable or slightly better toxicity profile. Taurine biosynthesis in frog retina: effects of light and dark adaptations. Single-voxel spectroscopy was carried out in right and left frontal lobe white matter, left parietal white matter and left occipital gray matter.

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Functional enrichment analysis and pathway enrichment analysis suggested that the immune response played a critical role in the progression of carotid atherosclerotic plaque. Therefore far reaching and continuous research to follow the further development of processes and results of participation is recommended. Adenylate cyclase activity of a 68,000-molecular-weight protein isolated from the outer membrane of Bordetella bronchiseptica. Assessment of environmental variables in Cauvery zonalon ointment for boils River and its tributaries. The pyrroloquinoline quinone (PQQ) coenzymes: a case of mistaken identity.

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coli strains, amoxi 1000 1a pharma pillet expression vectors and amino acid residues near the N-terminus, and is enhanced by a high cellular level of RimJ. These data suggest a common pathophysiological process for both coronary vasomotor abnormalities and microalbuminuria. All SCV clones had mutations in genes related to the electron-transport chain. Clinicians evaluating ex-preterm children with sleep disturbances should evaluate for RLS and PLMD. Lewis rats received orthotopic left lung transplantation from Lewis (syngeneic control) or Brown-Norway (major histocompatibility complex-mismatched allogeneic) donor rats.